Falck G, Rajs J
Department of Forensic Medicine, Karolinska Institute, Stockholm, Sweden.
J Child Neurol. 1995 Mar;10(2):123-6. doi: 10.1177/088307389501000212.
Increased brain weights have been reported in the literature to occur among infants who have died from sudden infant death syndrome, suggesting that cerebral edema might play a role in the cause of death among these children. We have compared brain weights from children between the ages of 1 week and 1 year, autopsied between 1980 and 1992. One group consisted of 125 victims of sudden infant death syndrome and the other of 38 children who had died with a diagnosis other than the sudden infant death syndrome. Brain weights from both groups exceeded the 50th percentile in previously published reference material. We were unable to show any significant differences between the groups in either the ratio between observed and expected brain weights or the ratio between brain weight and body weight. We conclude that there is no evidence for the notion that victims of sudden infant death syndrome have an increased brain weight. Other authors (in previous studies) may have overlooked the low overall weight at gestational age of prematurely born children while collecting data for reference levels. A revision of the figures seems to be necessary.
文献报道称，死于婴儿猝死综合征的婴儿大脑重量增加，这表明脑水肿可能在这些儿童的死因中起作用。我们比较了1980年至1992年间接受尸检的1周龄至1岁儿童的大脑重量。一组由125名婴儿猝死综合征受害者组成，另一组由38名诊断并非婴儿猝死综合征的死亡儿童组成。两组的大脑重量均超过了先前发表的参考资料中的第50百分位数。我们无法在两组之间观察到实际大脑重量与预期大脑重量之比或大脑重量与体重之比的任何显著差异。我们得出结论，没有证据支持婴儿猝死综合征受害者大脑重量增加这一观点。其他作者（在先前的研究中）在收集参考水平数据时，可能忽略了早产儿出生时总体重较低的情况。似乎有必要对这些数据进行修订。
