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The role of coronary angiography and coronary revascularization before noncardiac vascular surgery.

作者信息

Mason J J, Owens D K, Harris R A, Cooke J P, Hlatky M A

机构信息

Department of Health Research and Policy, Stanford University School of Medicine, CA 94305-5092, USA.

出版信息

JAMA. 1995 Jun 28;273(24):1919-25.

PMID:7783301
Abstract

OBJECTIVE

To determine whether preoperative coronary angiography and revascularization improve short-term outcomes in patients undergoing noncardiac vascular surgery.

DESIGN

Decision analysis.

PATIENTS

Patients undergoing elective vascular surgery who had either no angina or mild angina and a positive dipyridamole-thallium scan result.

INTERVENTIONS

Three strategies were compared. The first strategy was to proceed directly to vascular surgery. The second was to perform coronary angiography, followed by selective coronary revascularization, before proceeding to vascular surgery and to cancel vascular surgery in patients with severe inoperable coronary artery disease (CAD). The third was to perform coronary angiography, followed by selective coronary revascularization, before proceeding to vascular surgery and to perform vascular surgery in patients with inoperable CAD.

MAIN OUTCOME MEASURES

Mortality, nonfatal myocardial infarction, stroke, uncorrected vascular disease, and cost. All outcomes were assessed within 3 months.

RESULTS

Proceeding directly to vascular surgery led to lower morbidity and cost in the base case analysis. The coronary angiography strategy led to higher mortality if vascular surgery would proceed in patients with inoperable CAD, but led to slightly lower mortality if vascular surgery were canceled in patients with inoperable CAD. The coronary angiography strategy also led to lower mortality when vascular surgery was particularly risky.

CONCLUSIONS

Decision analysis indicates vascular surgery without preoperative coronary angiography generally leads to better outcomes. Preoperative coronary angiography should be reserved for patients whose estimated mortality from vascular surgery is substantially higher than average.

摘要

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