Harrington K A, Schindler M, Humphrey P P, Emson P C
Department of Neurobiology, Babraham Institute, Cambridge, UK.
Neurosci Lett. 1995 Mar 16;188(1):17-20. doi: 10.1016/0304-3940(95)11382-7.
The distribution and cellular localisation of somatostatin receptor subtype 4 (SSTR4) was investigated in the adult rat brain using the technique of in situ hybridisation with subtype specific oligonucleotide probes. Somatostatin receptor subtype 4 was found mainly in the hippocampus CA1 > CA2 > CA3 pyramidal cells and in the pyramidal cells in layers (IV-VI) of the cerebral cortex. Reverse transcription-PCR with SSTR4 specific primers confirmed the tissue distribution revealed by in situ hybridisation.