Kelion A D, Cockcroft J R, Ritter J M
Department of Clinical Pharmacology, UMDS, Guy's Hospital, London, UK.
Postgrad Med J. 1995 Apr;71(834):233-5. doi: 10.1136/pgmj.71.834.233.
The antiphospholipid syndrome is a thrombotic disorder which can occur in a primary form or more classically in systemic lupus erythematosus. An association between cryptogenic fibrosing alveolitis and the antiphospholipid syndrome has not previously been reported. We describe a patient with severe cryptogenic fibrosing alveolitis who developed pulmonary embolism and myocardial infarction in the presence of antiphospholipid antibody. The case also illustrates that worsening respiratory function may represent superimposition of one lung pathology on another, and may not simply be a deterioration of the pre-existing disease.
抗磷脂综合征是一种血栓形成性疾病，可呈原发性形式出现，或更典型地发生于系统性红斑狼疮中。隐源性纤维性肺泡炎与抗磷脂综合征之间的关联此前尚未见报道。我们描述了一名患有严重隐源性纤维性肺泡炎的患者，该患者在存在抗磷脂抗体的情况下发生了肺栓塞和心肌梗死。该病例还表明，呼吸功能恶化可能代表一种肺部病变叠加于另一种病变之上，而不一定仅仅是原有疾病的恶化。
