Savin H, Huberman M, Kott E, Lishner M, Kitai Y, Kidron D, Zissin R, Ravid M
Department of Medicine, Meir Hospital, Kfar Saba, Israel.
Br J Rheumatol. 1994 Oct;33(10):977-80. doi: 10.1093/rheumatology/33.10.977.
The spectrum of the primary antiphospholipid syndrome has expanded in recent years. It has been associated with a number of non-thrombotic syndromes such as pulmonary hypertension, adrenal insufficiency, chorea and avascular necrosis of bone. Yet, it has not been described in association with inflammatory pulmonary disease. We describe a young male with definite primary antiphospholipid syndrome who developed insidious diffuse pulmonary infiltrates. The histopathologic examination of the involved lung demonstrated alveolitis and fibrosis. We suggest that this pulmonary involvement may represent another manifestation of the primary antiphospholipid syndrome.
近年来，原发性抗磷脂综合征的范围有所扩大。它与许多非血栓形成性综合征相关，如肺动脉高压、肾上腺功能不全、舞蹈病和骨缺血性坏死。然而，它尚未被描述与炎症性肺部疾病相关。我们描述了一名患有明确原发性抗磷脂综合征的年轻男性，他出现了隐匿性弥漫性肺部浸润。受累肺部的组织病理学检查显示肺泡炎和纤维化。我们认为这种肺部受累可能代表原发性抗磷脂综合征的另一种表现形式。
