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[乙型肝炎(HBV)和丙型肝炎(HCV)病毒感染作为维持性血液透析患者慢性肝损伤的最终原因]

[Hepatitis B (HBV) and C (HCV) virus infections as an eventual cause of chronic hepatic damage in patients undergoing maintenance hemodialysis ].

作者信息

Slizien W, Michalik D, Własiuk M, Rutkowski B, Brylowska A

机构信息

Kliniki Chorób Nerek, Akademii Medycznej w Gdańsku.

出版信息

Przegl Lek. 1995;52(2):47-50.

PMID:7784615
Abstract

In 67 hemodialysis patients with high prevalence of HBV infection (64/67-95.5%) the occurrence of anti-HCV antibodies in second generation enzyme immunoassay was 61.2% (41/67). Among 40/67 (59.7%) patients with actually or previously detected biochemical signs of chronic hepatic injury the H Bs antigen or/and/anti-HCV antibodies were positive in 38 (95.0%) cases. High prevalence of HBV and HCV infections in studied population and their connection with biochemical signs of chronic hepatic injury shows the necessity of introduction the intensive prophylaxis of those infections in polish hemodialysis centers.

摘要

在67例乙肝病毒感染率较高(64/67,95.5%)的血液透析患者中,第二代酶免疫法检测抗丙肝病毒抗体的发生率为61.2%(41/67)。在67例中有40例(59.7%)患者有实际或既往检测到的慢性肝损伤生化指标,其中38例(95.0%)乙肝表面抗原或/和/抗丙肝病毒抗体呈阳性。研究人群中乙肝病毒和丙肝病毒感染的高发生率及其与慢性肝损伤生化指标的关联表明,在波兰血液透析中心有必要加强对这些感染的预防。

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