Yamada S, Maruoka T, Nagai K, Tsumura N, Yamada T, Sakata Y, Tominaga K, Motohiro T, Kato H, Makimura K
Department of Pediatrics, Kurume University School of Medicine, Japan.
Scand J Infect Dis. 1995;27(1):85-7. doi: 10.3109/00365549509018982.
During August and September, 1992, we experienced 4 cases of Hansenula anomala (H. anomala, synonym Pichia anomala) fungemia in immunocompromised patients. Two patients had been suffering from a malignant disease, 3 of them had received broad-spectrum antibiotics and a central venous catheter (CVC) had been inserted in all of them. H. anomala was isolated as the sole pathogen from all 4 patients. Three of them responded favorably to fluconazole after withdrawal of the catheter, but one failed. H. anomala should be considered as a possible cause of catheter-related infections.
1992年8月至9月期间，我们在免疫功能低下的患者中遇到了4例异常汉逊酵母（异常汉逊酵母，同义词异常毕赤酵母）菌血症病例。2例患者患有恶性疾病，其中3例接受了广谱抗生素治疗，并且所有患者均插入了中心静脉导管（CVC）。从所有4例患者中均分离出异常汉逊酵母作为唯一病原体。其中3例在拔除导管后对氟康唑反应良好，但1例无效。应将异常汉逊酵母视为导管相关感染的可能原因。
