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异常汉逊酵母引起的真菌血症:氟康唑治疗成功

Fungemia caused by Hansenula anomala: successful treatment with fluconazole.

作者信息

Hirasaki S, Ijichi T, Fujita N, Araki S, Gotoh H, Nakagawa M

机构信息

Second Department of Medicine, Kyoto Prefectural University of Medicine, Japan.

出版信息

Intern Med. 1992 May;31(5):622-4. doi: 10.2169/internalmedicine.31.622.

DOI:10.2169/internalmedicine.31.622
PMID:1324035
Abstract

Fungemia, due to Hansenula anomala, developed in an adult patient with small cell lung cancer who received anti-cancer chemotherapy and plasmapheresis for a sensori-motor neuropathy complication. Treatment with intravenous infusion of fluconazole in addition to the removal of the central venous catheter was successful in treating the fungemia. Pathogenic Hansenula anomala infections are rare, but reports of this infection have been increasing. The use of fluconazole treatment for this infection has not been reported in the literature, and this is the first case of an adult infection of Hansenula anomala in Japan.

摘要

一名成年小细胞肺癌患者在接受抗癌化疗和血浆置换治疗感觉运动神经病变并发症时,发生了由异常汉逊酵母引起的真菌血症。除拔除中心静脉导管外,静脉输注氟康唑治疗成功治愈了真菌血症。致病性异常汉逊酵母感染较为罕见,但此类感染的报告一直在增加。文献中尚未报道使用氟康唑治疗这种感染,这是日本首例成年异常汉逊酵母感染病例。

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