Besson I, Kinder M, Jou J M, Vives Corrons J L
Servei d'Hematologia Biològica, Hospital Clínic i Provincial, Universitat de Barcelona.
Sangre (Barc). 1995 Apr;40(2):103-7.
To evaluate three automated devices for measuring the erythrocyte sedimentation rate (ESR) (VES-MATIC 60, Menarini(R); SEDISCAN Becton-Dickinson(R) y SEDIMATIC, Ral(R)) by comparison with the Westergren method (WM).
A total of 1576 whole blood samples (VM: 694, SC: 316 and SM: 566) from patients of the Hospital Clínic i Provincial de Barcelona were included in this study. In all the specimens, the ESR was determined following the ICSH recommendations (WM). The Student's t test for paired data and linear regression analysis were used for inaccuracy study. Reproducibility was assessed after five measurements of three different samples and establishing the coefficient of variation (CV).
Significant correlation was found between the systems studied and th WM. Moreover, for ESR > 21 mm/h (groups II, III and IV) the results provided by VM system were not significantly different from those of WM. Finally, all the systems presented a good reproducibility, although the lower values of CV were obtained with the VM method.
The automatic systems for measurements of the ESR demonstrate important advantages and, from this analysis, we concluded that the VM could be the alternative method to conventional Westergren for the ESR determination.
通过与魏氏法（WM）比较，评估三种用于测量红细胞沉降率（ESR）的自动化设备（VES-MATIC 60，美纳里尼公司；SEDISCAN，贝克曼-迪金森公司；SEDIMATIC，拉尔公司）。
本研究纳入了巴塞罗那省立临床医院患者的1576份全血样本（VM：694份，SC：316份，SM：566份）。在所有样本中，按照国际血液学标准化委员会的建议（WM）测定ESR。采用配对数据的学生t检验和线性回归分析进行误差研究。在对三个不同样本进行五次测量并确定变异系数（CV）后评估重复性。
在所研究的系统与WM之间发现了显著相关性。此外，对于ESR>21 mm/h（第二、三、四组），VM系统提供的结果与WM的结果无显著差异。最后，所有系统均具有良好的重复性，尽管VM方法获得的CV值较低。
用于测量ESR的自动化系统显示出重要优势，从本分析中我们得出结论，VM可能是替代传统魏氏法测定ESR的方法。
