Day D G
Animal Health Center, College of Veterinary Medicine, Mississippi State University, Mississippi, USA.
Vet Clin North Am Small Anim Pract. 1995 Mar;25(2):375-85. doi: 10.1016/s0195-5616(95)50032-4.
Feline cholangiohepatitis complex causes a diffuse intrahepatic cholestasis of unknown etiology. Recognized histologic forms include acute suppurative cholangitis/cholangiohepatitis, long-term nonsuppurative cholangitis/cholangiohepatitis, and biliary cirrhosis. Treatment of cholangiohepatitis complex varies based on histologic type. Thus a liver biopsy is necessary for definitive diagnosis and treatment. Because cholangiohepatitis complex causes diffuse hepatic change, percutaneous needle biopsies are often sufficient for obtaining a diagnosis. Antibiotics are used to treat all forms of feline cholangiohepatitis complex, but steroids may be of equal or greater importance for use in the treatment of long-term nonsuppurative cholangiohepatitis. Prognosis is guarded for cats with any form of cholangiohepatitis complex due to the variable response to treatment seen in many cats. Spontaneous remission occasionally occurs.
猫胆汁性肝肝炎综合征会导致病因不明的弥漫性肝内胆汁淤积。公认的组织学类型包括急性化脓性胆管炎/胆汁性肝肝炎、长期非化脓性胆管炎/胆汁性肝肝炎和胆汁性肝硬化。胆汁性肝肝炎综合征的治疗因组织学类型而异。因此，肝活检对于明确诊断和治疗是必要的。由于胆汁性肝肝炎综合征会引起弥漫性肝脏变化，经皮穿刺活检通常足以获得诊断。抗生素用于治疗所有形式的猫胆汁性肝肝炎综合征，但类固醇在治疗长期非化脓性胆汁性肝肝炎中可能同样重要或更为重要。由于许多猫对治疗的反应不一，任何形式的胆汁性肝肝炎综合征的猫预后都不乐观。偶尔会出现自发缓解。
