Tell G S, Mittelmark M B, Hylander B, Shumaker S A, Russell G, Burkart J M
ANNA J. 1995 Jun;22(3):301-8; discussion 309-10.
To identify factors associated with health-related quality of life (HRQoL) in end stage renal disease (ESRD) patients treated with dialysis, and to identify potential racial differences in HRQoL.
Cross-sectional study. SAMPLE/SETTINGS: 256 dialysis patients; 72 black women, 59 black men, 61 white women, and 64 white men at Piedmont Dialysis Center, a university-affiliated dialysis center in northwest North Carolina.
Information was obtained on perceived social support, social networks, blood chemistries, blood pressure, cause of renal failure, treatment-related factors, and socioeconomic factors. HRQoL indicators included two measures of life satisfaction, limitations in leisure-time activities, and Karnofsky's Physical Functioning Scale.
On all HRQoL indicators, blacks consistently rated their HRQoL better than whites. In univariate analyses, lack of social support was consistently related to poorer HRQoL. In multivariate regression analyses, good social support and black race were the two strongest predictors of more positive responses to each of the HRQoL indicators, after controlling for the effects of the other investigated factors. With respect to the Karnofsky scale, younger age and fewer medications taken were additional significant predictors of better functioning.
HRQoL was consistently rated better among blacks than among whites. In addition, perceived social support exerted a strong, independent influence on objectively and subjectively measured HRQoL of ESRD patients.
确定接受透析治疗的终末期肾病(ESRD)患者中与健康相关生活质量(HRQoL)相关的因素,并确定HRQoL方面潜在的种族差异。
横断面研究。
样本/地点:256名透析患者;北卡罗来纳州西北部一家大学附属透析中心皮埃蒙特透析中心的72名黑人女性、59名黑人男性、61名白人女性和64名白人男性。
获取有关感知到的社会支持、社会网络、血液化学指标、血压、肾衰竭病因、治疗相关因素和社会经济因素的信息。HRQoL指标包括两项生活满意度测量、休闲活动受限情况以及卡诺夫斯基身体功能量表。
在所有HRQoL指标上,黑人对其HRQoL的评分始终高于白人。在单因素分析中,缺乏社会支持始终与较差的HRQoL相关。在多因素回归分析中,在控制其他调查因素的影响后,良好的社会支持和黑人种族是对每个HRQoL指标有更积极反应的两个最强预测因素。就卡诺夫斯基量表而言,年龄较小和服用药物较少是功能较好的另外两个重要预测因素。
黑人的HRQoL评分始终高于白人。此外,感知到的社会支持对ESRD患者客观和主观测量的HRQoL产生了强大的独立影响。