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1
Torque generation by the flagellar rotary motor.鞭毛旋转马达产生的扭矩。
Biophys J. 1995 Apr;68(4 Suppl):163S-166S; discussion 166S-167S.
2
Study of the torque of the bacterial flagellar motor using a rotating electric field.利用旋转电场研究细菌鞭毛马达的扭矩
Biophys J. 1993 Mar;64(3):925-33. doi: 10.1016/S0006-3495(93)81454-1.
3
Torque generated by the flagellar motor of Escherichia coli while driven backward.大肠杆菌鞭毛马达在反向驱动时产生的扭矩。
Biophys J. 1999 Jan;76(1 Pt 1):580-7. doi: 10.1016/S0006-3495(99)77226-7.
4
Constraints on models for the flagellar rotary motor.鞭毛旋转马达模型的限制因素。
Philos Trans R Soc Lond B Biol Sci. 2000 Apr 29;355(1396):491-501. doi: 10.1098/rstb.2000.0590.
5
Abrupt changes in flagellar rotation observed by laser dark-field microscopy.通过激光暗场显微镜观察到鞭毛旋转的突然变化。
Nature. 1990 Aug 16;346(6285):677-80. doi: 10.1038/346677a0.
6
Torque generated by the flagellar motor of Escherichia coli.大肠杆菌鞭毛马达产生的扭矩。
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Limiting (zero-load) speed of the rotary motor of is independent of the number of torque-generating units.的旋转电机的限速(空载)与产生扭矩的单元数量无关。
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Mannose-Binding Lectin Inhibits the Motility of Pathogenic Salmonella by Affecting the Driving Forces of Motility and the Chemotactic Response.甘露糖结合凝集素通过影响运动驱动力和趋化反应来抑制致病性沙门氏菌的运动。
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Roles of the intramolecular disulfide bridge in MotX and MotY, the specific proteins for sodium-driven motors in Vibrio spp.分子内二硫键在MotX和MotY中的作用,MotX和MotY是弧菌属中钠驱动马达的特定蛋白质。
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本文引用的文献

1
Genetic and biochemical analysis of Salmonella typhimurium FliI, a flagellar protein related to the catalytic subunit of the F0F1 ATPase and to virulence proteins of mammalian and plant pathogens.鼠伤寒沙门氏菌FliI的遗传与生化分析,FliI是一种鞭毛蛋白,与F0F1 ATP酶的催化亚基以及哺乳动物和植物病原体的毒力蛋白相关。
J Bacteriol. 1993 May;175(10):3131-8. doi: 10.1128/jb.175.10.3131-3138.1993.
2
Isolation, characterization and structure of bacterial flagellar motors containing the switch complex.含开关复合体的细菌鞭毛马达的分离、特性分析及结构研究
J Mol Biol. 1994 Jan 28;235(4):1261-70. doi: 10.1006/jmbi.1994.1079.
3
Torque generated by the flagellar motor of Escherichia coli.大肠杆菌鞭毛马达产生的扭矩。
Biophys J. 1993 Nov;65(5):2201-16. doi: 10.1016/S0006-3495(93)81278-5.
4
Sensing structural intermediates in bacterial flagellar assembly by export of a negative regulator.通过输出负调控因子来感知细菌鞭毛组装中的结构中间体。
Science. 1993 Nov 19;262(5137):1277-80. doi: 10.1126/science.8235660.
5
Domain structures of the MS ring component protein (FliF) of the flagellar basal body of Salmonella typhimurium.鼠伤寒沙门氏菌鞭毛基体的MS环组件蛋白(FliF)的结构域结构
J Mol Biol. 1994 Feb 18;236(2):546-55. doi: 10.1006/jmbi.1994.1164.
6
The C-terminal sequence conservation between OmpA-related outer membrane proteins and MotB suggests a common function in both gram-positive and gram-negative bacteria, possibly in the interaction of these domains with peptidoglycan.OmpA相关外膜蛋白与MotB之间的C末端序列保守性表明,在革兰氏阳性菌和革兰氏阴性菌中存在共同功能,可能在于这些结构域与肽聚糖的相互作用。
Mol Microbiol. 1994 Apr;12(2):333-4. doi: 10.1111/j.1365-2958.1994.tb01021.x.
7
Energetics of flagellar rotation in bacteria.细菌鞭毛旋转的能量学
J Mol Biol. 1980 Apr 15;138(3):541-61. doi: 10.1016/s0022-2836(80)80017-9.
8
Isotope and thermal effects in chemiosmotic coupling to the flagellar motor of Streptococcus.化学渗透偶联到链球菌鞭毛马达中的同位素和热效应。
Cell. 1983 Mar;32(3):913-9. doi: 10.1016/0092-8674(83)90076-4.
9
Chemical modification of Streptococcus flagellar motors.链球菌鞭毛马达的化学修饰。
J Bacteriol. 1984 Jun;158(3):832-43. doi: 10.1128/jb.158.3.832-843.1984.
10
Successive incorporation of force-generating units in the bacterial rotary motor.细菌旋转马达中力产生单元的连续整合。
Nature. 1984;309(5967):470-2. doi: 10.1038/309470a0.

鞭毛旋转马达产生的扭矩。

Torque generation by the flagellar rotary motor.

作者信息

Berg H C

机构信息

Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

出版信息

Biophys J. 1995 Apr;68(4 Suppl):163S-166S; discussion 166S-167S.

PMID:7787060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1281903/
Abstract

A review is given of the structure and dynamics of the flagellar rotary motor. Force-generating elements in a motor driving a tethered bacterium (a cell fixed to the substratum by a single flagellum) exert forces of order 20 pN while moving at speeds of order 1 micron/s. Force-generating elements in a motor driving a flagellar filament in a bundle exert forces some 10-fold lower but move at speeds more than 10-fold higher. The motor torque-speed relationship has been measured over a wide dynamic range. Motors strongly resist being driven backwards and are easily broken.

摘要

本文综述了鞭毛旋转马达的结构和动力学。驱动拴系细菌(通过单根鞭毛固定在基质上的细胞)的马达中的力产生元件在以约1微米/秒的速度移动时施加约20皮牛的力。驱动成束鞭毛丝的马达中的力产生元件施加的力约低10倍,但移动速度高出10倍以上。已在很宽的动态范围内测量了马达的扭矩-速度关系。马达强烈抵抗向后驱动且容易损坏。