Berg H C
Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Biophys J. 1995 Apr;68(4 Suppl):163S-166S; discussion 166S-167S.
A review is given of the structure and dynamics of the flagellar rotary motor. Force-generating elements in a motor driving a tethered bacterium (a cell fixed to the substratum by a single flagellum) exert forces of order 20 pN while moving at speeds of order 1 micron/s. Force-generating elements in a motor driving a flagellar filament in a bundle exert forces some 10-fold lower but move at speeds more than 10-fold higher. The motor torque-speed relationship has been measured over a wide dynamic range. Motors strongly resist being driven backwards and are easily broken.
本文综述了鞭毛旋转马达的结构和动力学。驱动拴系细菌(通过单根鞭毛固定在基质上的细胞)的马达中的力产生元件在以约1微米/秒的速度移动时施加约20皮牛的力。驱动成束鞭毛丝的马达中的力产生元件施加的力约低10倍,但移动速度高出10倍以上。已在很宽的动态范围内测量了马达的扭矩-速度关系。马达强烈抵抗向后驱动且容易损坏。