Pettit R K, Martin E S, Wagner S M, Bertolino V J
Department of Biology, State University of New York College at Potsdam 13676, USA.
Infect Immun. 1995 Jul;63(7):2773-5. doi: 10.1128/iai.63.7.2773-2775.1995.
Neisseria gonorrhoeae infects a diverse array of niches in its human host, which expose the organism to dramatic variations in pH. We examined growth and lipooligosaccharide expression of two gonococcal strains in liquid and solid cultures under acidic, neutral, and alkaline conditions. Growth rates in broth were similar under the three conditions, and the pH remained fairly constant throughout the growth cycle. Altered lipooligosaccharide expression at the different pHs was noted in both plate- and broth-grown organisms.
淋病奈瑟菌在其人类宿主中感染多种生态位，这使该生物体暴露于pH值的巨大变化中。我们研究了两种淋球菌菌株在酸性、中性和碱性条件下的液体和固体培养物中的生长及脂寡糖表达情况。在这三种条件下，肉汤中的生长速率相似，并且在整个生长周期中pH值保持相当稳定。在平板培养和肉汤培养的生物体中均观察到不同pH值下脂寡糖表达的改变。
