Møller H, Jørgensen N, Forman D
Unit of Carcinogen Identification and Evaluation, International Agency for Research on Cancer, Lyon, France.
Int J Cancer. 1995 Jun 9;61(6):761-4. doi: 10.1002/ijc.2910610604.
Several epidemiological studies have described increasing trends over time in the incidence of testicular cancer in adult men. Less attention has been given to the trends in young boys, adolescents and old men. This paper describes the incidence of testicular cancer in young boys (0-4 years) and adolescents (15-19 years) in Denmark, Norway and Sweden, and compares these trends with the corresponding data on adults. Although only small numbers were available, the data suggest that the incidence of testicular cancer in young boys has been constant, at a level around 0.5 per 100,000. This observation lends support to the idea that testicular cancer in young boys is aetiologically distinct from testicular cancer in adults. In all three populations we found a particularly high average annual increase in the incidence of testicular cancer in adolescents (around 6% per year). It is proposed that this increase is mainly caused by a secular trend towards earlier age at puberty.
多项流行病学研究表明，成年男性睾丸癌的发病率随时间呈上升趋势。而针对男童、青少年及老年男性的发病趋势则较少受到关注。本文描述了丹麦、挪威和瑞典男童（0至4岁）及青少年（15至19岁）睾丸癌的发病率，并将这些趋势与成年人的相应数据进行比较。尽管可用数据较少，但数据表明男童睾丸癌的发病率一直保持稳定，约为每10万人0.5例。这一观察结果支持了这样一种观点，即男童睾丸癌在病因上与成年男性睾丸癌不同。在这三个人口中，我们均发现青少年睾丸癌发病率的年平均增幅特别高（每年约6%）。据推测，这种增加主要是由青春期年龄提前的长期趋势导致的。
