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[儿童及青少年气管隆突的切除与重建]

[Resection and reconstruction of the carina in children and adolescents].

作者信息

Gaissert H A, Grillo H C, Mathisen D J, Wain J C

机构信息

Washington University Department of Surgery, Barnes Hospital, St. Louis, MO 63110, USA.

出版信息

Langenbecks Arch Chir. 1995;380(3):166-70. doi: 10.1007/BF00207724.

Abstract

While resection of tracheobronchial segments has become a standard operation in adults, lesions of the carina in children are rare and their treatment is technically more demanding. Since 1980, 8 patients aged 8 to 19 years underwent surgical reconstruction of the carina. The indications were tumors in 5 and non-neoplastic lesions in 3. In 3 patients with tumor (2) and advanced histoplasmosis (1), resection of the carina was combined with parenchymal resection. The principles of operative repair include complete resection, with frozen section confirmation in tumors, particular emphasis on adequate mobilization of the airway in children to reduce anastomotic tension, and use of anesthetic techniques that facilitate early extubation. One patient (12.5%) died after complex airway reconstruction for extensive mediastinal fibrosis. Residual malacia in a patient with postpneumonectomy syndrome required successful re-resection. Seven patients remain free of anastomotic stricture and tumor recurrence during a mean follow-up of 62 months (range 5 to 132 months), with expected preservation of lung function. Late bronchoscopy in 5 patients 6 months to 11 years after operation demonstrated growth of the luminal diameter and patent anastomoses. Carinal reconstruction in children is occasionally required, succeeds in general, and does not result in late problems at the anastomosis.

摘要

虽然气管支气管段切除术已成为成人的标准手术,但儿童气管隆突病变罕见,其治疗在技术上要求更高。自1980年以来,8例年龄在8至19岁的患者接受了气管隆突的手术重建。适应证为5例肿瘤和3例非肿瘤性病变。在3例肿瘤患者(2例)和晚期组织胞浆菌病患者(1例)中,气管隆突切除与实质切除相结合。手术修复的原则包括完整切除,肿瘤患者术中行冰冻切片确认,特别强调充分游离儿童气道以降低吻合口张力,以及采用有助于早期拔管的麻醉技术。1例患者(12.5%)因广泛纵隔纤维化行复杂气道重建后死亡。1例肺叶切除术后综合征患者残留软化灶,需再次成功切除。7例患者在平均62个月(5至132个月)的随访中未出现吻合口狭窄和肿瘤复发,肺功能有望保留。5例患者在术后6个月至11年进行的晚期支气管镜检查显示管腔直径增大,吻合口通畅。儿童气管隆突重建偶尔需要进行,总体上是成功的,且不会导致吻合口后期出现问题。

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