Markestad T, Skadberg B, Hordvik E, Morild I, Irgens L M
Department of Paediatrics, University of Bergen, Norway.
Acta Paediatr. 1995 Apr;84(4):375-8. doi: 10.1111/j.1651-2227.1995.tb13653.x.
The proportion of prone sleeping among sudden infant death syndrome (SIDS) victims and infants in general, and the rate of SIDS were prospectively studied in the county of Hordaland, Norway, three years before (1987-89) and three years after (1990-92) a campaign to discourage prone sleeping. Before the campaign, 64% of random reference infants were put prone versus 8% after (p < 0.0001). Concurrently, the rate of SIDS decreased from 3.5 to 1.6 per 1000 live births (63 infants before and 30 after the campaign, p = 0.0002). Prone sleeping was not considered a statistically significant risk factor for SIDS before (OR 2.0, 95% CI 0.8-4.5), but was highly significant (OR 11.3, 95% CI 3.6-36.5) after the campaign. Prone sleeping is an important risk factor for SIDS, but the association may be missed in epidemiological studies if prone is the predominant sleeping position. Behaviour with regard to sleeping position may be changed rapidly by means of a simple campaign.
在挪威霍达兰郡,对婴儿猝死综合征(SIDS)受害者及普通婴儿中俯卧睡眠的比例,以及SIDS发生率进行了前瞻性研究。研究时段为一项劝阻俯卧睡眠运动开展前三年(1987 - 1989年)及开展后三年(1990 - 1992年)。运动开展前,随机抽取的对照婴儿中有64%采用俯卧睡眠,运动开展后这一比例为8%(p < 0.0001)。与此同时,SIDS发生率从每1000例活产3.5例降至1.6例(运动开展前63例,运动开展后30例,p = 0.0002)。运动开展前,俯卧睡眠未被视为SIDS的统计学显著风险因素(比值比2.0,95%置信区间0.8 - 4.5),但运动开展后具有高度显著性(比值比11.3,95%置信区间3.6 - 36.5)。俯卧睡眠是SIDS的一个重要风险因素,但如果俯卧是主要睡眠姿势,在流行病学研究中可能会遗漏这种关联。通过一项简单的运动,关于睡眠姿势的行为可能会迅速改变。