含氯己定的抗菌肥皂对皮肤微生物菌群的影响。
Effect of antimicrobial soap containing chlorhexidine on the microbial flora of skin.
作者信息
Aly R, Maibach H I
出版信息
Appl Environ Microbiol. 1976 Jun;31(6):931-5. doi: 10.1128/aem.31.6.931-935.1976.
The qualitative and semiquantitative changes in the aerobic microbial flora of normal skin with the prolonged use of a chlorhexidine scrub (6 months) were investigated. More samples in the chlorhexidine scrub group had gram-negative bacilli in their axilla (63 of 96, 66%) and groin (36 of 96, 38%) than the controls (32 of 66, 49%, for axilla and 7 of 66, 11%, for groin; P = 0.01). Klebsiella and Enterobacter were the predominant organisms in the control and chlorhexidine groups, respectively. The chlorhexidine scrub produced a reduction in the total aerobic counts in the axilla, groin, and between the toes and the fingers. Fewer samples from the chlorhexidine-treated areas revealed the presence of lipophilic diphtheroids than did the controls. Lipophilic diphteroids were also reduced quantitatively in the groin and axilla with chlorhexidine treatment. No consistent pattern for the other major groups of bacteria was noted between the treatments.
研究了长期使用洗必泰擦洗剂（6个月）对正常皮肤需氧微生物菌群的定性和半定量变化。与对照组相比，洗必泰擦洗剂组更多样本在腋窝（96个中有63个，66%）和腹股沟（96个中有36个，38%）检出革兰氏阴性杆菌，对照组腋窝为66个中有32个，49%，腹股沟为66个中有7个，11%；P = 0.01）。克雷伯菌属和肠杆菌属分别是对照组和洗必泰组中的主要微生物。洗必泰擦洗剂使腋窝、腹股沟以及脚趾间和手指间的需氧菌总数减少。与对照组相比，来自洗必泰处理区域的样本中亲脂性类白喉杆菌的存在较少。洗必泰处理后，腹股沟和腋窝中的亲脂性类白喉杆菌数量也有所减少。在不同处理之间，未观察到其他主要细菌组的一致模式。
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