Department of Neurology, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle Upon Tyne, UK.
Nat Sci Sleep. 2013 May 31;5:61-75. doi: 10.2147/NSS.S34842. Print 2013.
Sleep has been described as being of the brain, by the brain, and for the brain. This fundamental neurobiological behavior is controlled by homeostatic and circadian (24-hour) processes and is vital for normal brain function. This review will outline the normal sleep-wake cycle, the changes that occur during aging, and the specific patterns of sleep disturbance that occur in association with both mental health disorders and neurodegenerative disorders. The role of primary sleep disorders such as insomnia, obstructive sleep apnea, and REM sleep behavior disorder as potential causes or risk factors for particular mental health or neurodegenerative problems will also be discussed.
睡眠被描述为大脑的、由大脑控制的和为大脑服务的。这种基本的神经生物学行为受稳态和昼夜节律（24 小时）过程的控制，对大脑的正常功能至关重要。本文将概述正常的睡眠-觉醒周期、衰老过程中的变化以及与心理健康障碍和神经退行性疾病相关的特定睡眠障碍模式。原发性睡眠障碍（如失眠、阻塞性睡眠呼吸暂停和 REM 睡眠行为障碍）作为特定心理健康或神经退行性问题的潜在原因或危险因素的作用也将进行讨论。
