Yoshida K, Koba H, Igarashi T, Nakagawa A, Nishiyama K, Harada H, Saitoh T, Abe S
Third Department of Internal Medicine, Sapporo Medical University, School of Medicine, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Sep;32(9):856-60.
Morphological features of Swyer-James syndrome were studied in a specimen obtained during left pneumonectomy. A 67-year-old woman was admitted because her left lung was hyperlucent and contained a solitary nodule. Primary lung adenocarcinoma complicated with Swyer-James syndrome was diagnosed, and left pneumonectomy done. The left upper lobe was inflated and fixed for morphological study. The volume of the specimen was obviously lower than normal but the bronchial branching was normal. Macroscopically, the specimen had irregular bronchial walls, bronchiectatic changes, and dilation of distal air spaces, similar to panlobular emphysema. Microscopically, there was scarring in periarteriolar regions that suggested bronchiolitis obliterans, enlargement of distal airspaces, and an abnormally low number of capillaries. These findings suggest hypoplasia of the lung due to abnormal lung growth after birth.
在左肺切除术中获取的标本上研究了斯怀尔-詹姆斯综合征的形态学特征。一名67岁女性因左肺透亮度增加且有一个孤立结节而入院。诊断为原发性肺腺癌合并斯怀尔-詹姆斯综合征，并进行了左肺切除术。将左上叶充气并固定以进行形态学研究。标本体积明显低于正常，但支气管分支正常。宏观上，标本有不规则的支气管壁、支气管扩张改变以及远端气腔扩张，类似于全小叶型肺气肿。微观上，小动脉周围区域有瘢痕形成，提示闭塞性细支气管炎、远端气腔扩大以及毛细血管数量异常减少。这些发现提示出生后肺生长异常导致肺发育不全。
