Behera D, Dash S, Sen S
Department of Pulmonary Medicine, Post-Graduate Institute of Medical Education & Research, Chandigarh, India.
Respiration. 1994;61(5):269-73. doi: 10.1159/000196350.
Myeloperoxidase (MPO) level and MPO scoring were estimated in Indian bidi smokers and compared with those in cigarette smokers and non-smokers. The values were higher in the neutrophils of 20 bidi smokers compared to 20 age-matched non-smokers (p < 0.001). However, they were similar to those in 20 cigarette smokers. No correlation of MPO activity was observed with blood carboxyhaemoglobin levels and smoking indices except in bidi smokers. Total leucocyte count and total neutrophil counts were also higher in bidi and cigarette smokers. This increased MPO activity in the neutrophils of bidi and cigarette smokers may contribute to the greater risk of obstructive pulmonary disease.
对印度比迪烟吸烟者的髓过氧化物酶（MPO）水平和MPO评分进行了评估，并与卷烟吸烟者和非吸烟者进行了比较。与20名年龄匹配的非吸烟者相比，20名比迪烟吸烟者中性粒细胞中的MPO值更高（p < 0.001）。然而，这些值与20名卷烟吸烟者的MPO值相似。除比迪烟吸烟者外，未观察到MPO活性与血液中碳氧血红蛋白水平及吸烟指数之间存在相关性。比迪烟吸烟者和卷烟吸烟者的白细胞总数和中性粒细胞总数也更高。比迪烟吸烟者和卷烟吸烟者中性粒细胞中MPO活性的增加可能导致患阻塞性肺病的风险更高。
