Heite H J, Maucher O M
Dermatologica. 1976;152(1):8-15.
Thirty-four married couples with clinically unexplained infertility and normal spermiograms in all male partners were investigated for sperm antibodies by means of the sperm agglutination, sperm immobilization and sperm immunofluorescence test. In 50% of the couples, sperm antibodies were found in at least one of the partners and with at least one of the tests, e.g. ten times in the female partner alone, six times in the male partner alone, and once in both partners. The correspondance of the three tests was astonishingly low; it is assumed, therefore, that they indicate different types of antibodies. On the basis of the present investigations it is not possible to assess which type of antibody is responsible for the infertility of the female or male partner respectively. This seems only possible when the decrease of certain antibody types can be determined after a period of no antigen contact (avoidance of sperm contact) and when conception has taken place. The significance of autoantibodies against sperm in clinically healthy men with normal spermiograms remains open.
对34对已婚夫妇进行了研究，这些夫妇临床上存在不明原因的不孕症，且所有男性伴侣的精子图均正常，通过精子凝集试验、精子制动试验和精子免疫荧光试验检测精子抗体。在50%的夫妇中，至少一方伴侣通过至少一种检测方法发现了精子抗体，例如仅在女性伴侣中发现10次，仅在男性伴侣中发现6次，双方伴侣中均发现1次。这三种检测方法的一致性出奇地低；因此可以推测，它们检测的是不同类型的抗体。基于目前的研究，无法评估哪种类型的抗体分别导致女性或男性伴侣的不孕。只有在经过一段时间无抗原接触（避免精子接触）后某些抗体类型减少且已受孕时，才有可能确定这一点。精子自身抗体在精子图正常的临床健康男性中的意义尚不清楚。
