Siewert C, Siewert H, Winterfeld H J, Strangfeld D
Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Charité, Medizinische Fakultät der Humboldt-Universität zu Berlin.
Z Kardiol. 1994 Sep;83(9):652-7.
Effective treatment of hypertension includes decrease of blood pressure at rest, dynamic and isometric exercise. Therefore, we investigated the hemodynamic changes by radiocardiography (central hemodynamic) and Xenon-133-muscle clearance (peripheral hemodynamic) before and after a sauna treatment during a period of 3 months. 46 hypertensive men (WHO I-II, aged 41 +/- 11 years) participated in the study. Systolic and diastolic blood pressure at rest and during dynamic exercise were decreased significantly (p < or = 0.01) by sauna therapy. Change of blood pressure at isometric exercise was not significant (from 157.5 +/- 16.5 mmHg to 155.0 +/- 15.4 mmHg). The changes of cardiac output and total peripheral resistance were also not significant. Half-time of muscle clearance decreased significantly (from 4.4 +/- 1.9 min to 3.2 +/- 1.2 min, p < or = 0.01) and functional cross-section A increased significantly (from 3.8 +/- 0.9 mm2.c to 4.4 +/- 0.9 mm2.c, p < or = 0.01) after the sauna therapy at dynamic exercise, but not at isometric exercise. These results show the changes between isometric and dynamic exercise, which can only be explained well by a study of peripheral hemodynamic. Contrary to dynamic exercise, sauna therapy did not significantly decrease blood pressure at isometric exercise.
高血压的有效治疗包括降低静息血压、进行动态和等长运动。因此，我们通过放射性心动描记法（中心血流动力学）和氙-133-肌肉清除率（外周血流动力学）研究了3个月期间桑拿治疗前后的血流动力学变化。46名高血压男性（世界卫生组织I-II级，年龄41±11岁）参与了该研究。桑拿疗法使静息和动态运动时的收缩压和舒张压显著降低（p≤0.01）。等长运动时血压变化不显著（从157.5±16.5 mmHg降至155.0±15.4 mmHg）。心输出量和总外周阻力的变化也不显著。动态运动时桑拿治疗后肌肉清除半衰期显著缩短（从4.4±1.9分钟降至3.2±1.2分钟，p≤0.01），功能横截面积A显著增加（从3.8±0.9 mm2.c增至4.4±0.9 mm2.c，p≤0.01），但等长运动时未出现此情况。这些结果显示了等长运动和动态运动之间的变化，这只能通过外周血流动力学研究得到很好的解释。与动态运动相反，桑拿疗法在等长运动时并未显著降低血压。
