Grishin V V, Vyzhigina M A
Anesteziol Reanimatol. 1994 Jul-Aug(4):24-7.
Two schemes of anesthesia were used in 34 patients, making use of beforal, an agonist-antagonist of opioid receptors, as an analgesic component of total anesthesia during operations on the lungs. To improve neurovegetative protection, adrenomimetic clofelin was added to the Ist scheme and neuroleptic droperidol to the IInd. Use of beforal as an analgesic component of balanced total anesthesia in thoracal surgery in combination with both clofelin and droperidol ensured a sufficient level of anesthesiologic protection. Combination of beforal with clofelin, however, prevented hyperdynamic circulatory reactions at traumatic stages of the operation and intubation of the trachea and stabilized thermal homeostasis parameters, this indicating a more potent neurovegetative protection in this scheme of anesthesia.
对34例患者采用了两种麻醉方案,在肺部手术期间使用阿片受体激动 - 拮抗剂倍福雷作为全麻醉的镇痛成分。为了加强神经植物性保护,第一种方案中加入了拟肾上腺素药氯苯福林,第二种方案中加入了抗精神病药氟哌利多。在胸外科手术中,将倍福雷作为平衡全麻醉的镇痛成分与氯苯福林和氟哌利多联合使用,确保了足够水平的麻醉保护。然而,倍福雷与氯苯福林联合使用,在手术的创伤阶段和气管插管时可预防高动力循环反应,并稳定热稳态参数,这表明该麻醉方案具有更强的神经植物性保护作用。