Zhao X, Dong Z, Yang Z
Department of Otorhinolaryngology, First Affiliated Hospital, Bethune University of Medical Sciences, Changchun.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1994;29(2):98-100.
The histomorphological influences of ovariectomies and estradiol injections on the nasal mucosa were observed in adult female guinea pigs. In the mucosa of ovariectomized guinea pigs, degenerative changes including dissolving and desquamation of cilia and glandular hypotrophy were found. On the contrary, thickening layer of the epithelium, spongiosis and edema of the corium, hyperplasia of glands and increased density of cilia were observed in the mucosa of guinea pigs receiving estrogen. The results demonstrated that different levels of estrogen might have different effects on the nasal mucosa.
在成年雌性豚鼠中观察了卵巢切除术和注射雌二醇对鼻黏膜的组织形态学影响。在去卵巢豚鼠的黏膜中，发现了包括纤毛溶解和脱落以及腺体萎缩在内的退行性变化。相反，在接受雌激素的豚鼠黏膜中，观察到上皮增厚、真皮层海绵形成和水肿、腺体增生以及纤毛密度增加。结果表明，不同水平的雌激素可能对鼻黏膜有不同影响。
