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QT离散度:方法学问题与临床意义

QT dispersion: problems of methodology and clinical significance.

作者信息

Statters D J, Malik M, Ward D E, Camm A J

机构信息

Cardiological Sciences Department, St. George's Hospital Medical School, London, United Kingdom.

出版信息

J Cardiovasc Electrophysiol. 1994 Aug;5(8):672-85. doi: 10.1111/j.1540-8167.1994.tb01190.x.

DOI:10.1111/j.1540-8167.1994.tb01190.x
PMID:7804520
Abstract

QT dispersion is defined as the difference in QT interval between the different leads of the surface 12-lead ECG. This may provide an indirect measure of the underlying inhomogeneity of myocardial repolarization, which is believed to be important in arrhythmogenesis. Methodology for determining QT dispersion varies significantly between studies, and the results of these studies need to be interpreted in light of the methodology used. Although QT dispersion is developing into an important research tool, as yet it has no established role in clinical practice. Once standardization of methodology is achieved a clinical role may emerge, particularly in the assessment of patients before and after intervention aimed at reduction of arrhythmia risk.

摘要

QT离散度定义为体表12导联心电图不同导联之间QT间期的差值。这可能提供心肌复极潜在不均一性的间接测量指标,而心肌复极不均一性被认为在心律失常的发生中起重要作用。不同研究中测定QT离散度的方法差异很大,这些研究结果需要根据所使用的方法来解读。尽管QT离散度正在发展成为一种重要的研究工具,但目前它在临床实践中尚未确立其作用。一旦实现方法学的标准化,其临床作用可能会显现出来,特别是在评估旨在降低心律失常风险的干预措施前后的患者时。

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