Cawthron P, James A, Dell J, Seagroatt V
Thorneywood Child and Adolescent Psychiatry Unit, Nottingham, U.K.
J Child Psychol Psychiatry. 1994 Oct;35(7):1321-32. doi: 10.1111/j.1469-7610.1994.tb01237.x.
58 psychotic adolescents between the ages of 12 and 17 diagnosed according to RDC criteria were matched with psychiatric comparisons and followed-up using a two stage design. Information upon the group as a whole was obtained using death records, criminal records and data from the Oxford Record Linkage System. A sub-sample of 21 matched pairs were interviewed using the Schedule for Affective Disorders and Schizophrenia--Life time version (SADS-L) and the Adult Personality Functioning Assessment (APFA). The outcome of adolescent schizophrenia was poor with 78% continuously ill and socially handicapped. Outcome was better for bipolar disorders and schizo-affective disorders and similar to psychiatric comparisons.
根据研究诊断标准(RDC)确诊的58名年龄在12至17岁之间的精神病青少年与精神疾病对照组进行匹配,并采用两阶段设计进行随访。通过死亡记录、犯罪记录以及牛津记录链接系统的数据获取了整个组的信息。使用情感障碍与精神分裂症日程表——终生版(SADS-L)和成人人格功能评估(APFA)对21对匹配样本进行了访谈。青少年精神分裂症的预后较差,78%的患者持续患病且存在社会功能障碍。双相情感障碍和分裂情感性障碍的预后较好,与精神疾病对照组相似。