Vargha-Khadem F, Isaacs E, Muter V
Neurosciences Unit, Wolfson Centre, Mecklenburgh Square, London.
J Child Neurol. 1994 Oct;9 Suppl 2:67-73.
Views on human brain organization early in development have swung back and forth between the extreme notions of complete equipotentiality and adult-like specialization. Recent research on the cognitive effects of early brain damage supports an intermediate position and suggests that many claims on the older literature must be re-examined in the light of new evidence that cognitive impairments are sometimes attributable to previously ignored factors, such as a history of seizures, time since injury, and unsuspected lesions that are now detectable with neuroimaging techniques.
早期关于人类大脑发育过程中组织形式的观点，在完全等势性和类似成人的专门化这两种极端概念之间摇摆不定。近期关于早期脑损伤认知影响的研究支持了一种中间立场，并表明鉴于新证据，许多旧文献中的观点必须重新审视，这些新证据表明认知障碍有时可归因于先前被忽视的因素，如癫痫发作史、受伤后的时间以及现在通过神经成像技术可检测到的未被怀疑的病变。
