Yeatts R P
Department of Ophthalmology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina.
Med Clin North Am. 1995 Jan;79(1):195-209. doi: 10.1016/s0025-7125(16)30092-x.
Graves' ophthalmopathy is an organ-specific autoimmune process strongly linked to Graves' hyperthyroidism. Although the hyperthyroidism can be successfully treated, it is often the ophthalmopathy that produces the greatest long-term disability for patients suffering from this disease. Eyelid retraction, proptosis, periorbital edema, chemosis, and disturbances of ocular motility have both cosmetic and functional consequences. In some cases, the disease may progress to visual loss by exposure keratopathy or compressive optic neuropathy. This article discusses the manifestations of Graves' ophthalmopathy that require urgent attention and the relationship of the activity of Graves' ophthalmopathy to thyroid function status.
格雷夫斯眼病是一种器官特异性自身免疫过程，与格雷夫斯甲亢密切相关。虽然甲亢可以得到成功治疗，但对于患有这种疾病的患者来说，往往是眼病造成了最大的长期残疾。眼睑退缩、眼球突出、眶周水肿、球结膜水肿以及眼球运动障碍都有美容和功能方面的影响。在某些情况下，该疾病可能会因暴露性角膜病变或压迫性视神经病变而进展为视力丧失。本文讨论了格雷夫斯眼病需要紧急关注的表现以及格雷夫斯眼病的活动与甲状腺功能状态之间的关系。
