Gueglio B, de Gentile L, Nguyen J M, Achard J, Chabasse D, Marjolet M
Laboratoire de Parasitologie Pathologie Exotique, Faculté de Médicine, Nantes, France.
Parasitol Res. 1994;80(6):531-6. doi: 10.1007/BF00932703.
Toxocara canis is a common parasite in puppies. The danger to human health has not been properly established. We estimated the current incidence of this pathogen in two western districts of France, Loire-Atlantique and Maine et Loire. Blood samples from 1836 eosino-philic patients were collected and tested by an enzyme-linked immunosorbent assay (ELISA) excretory-secretory Toxocara antigen test. We obtained positive results in 22% of the cases and highly positive results in 7%. The ELISA data seemed to be age-dependent, with older patients having more positive results (P < 0.0001). The interlaboratory distribution of positive test results was statistically significantly different (P < 0.0001), suggesting regional sources. The main clinical expressions of toxocariasis were: asthenia, gastric pain, and pulmonary disease. Individual and collective surveys of this zoonotic disease need to be carried out.
犬弓首蛔虫是幼犬常见的寄生虫。其对人类健康的危害尚未得到确切证实。我们估算了法国西部两个地区——大西洋卢瓦尔省和曼恩-卢瓦尔省——这种病原体的当前发病率。采集了1836例嗜酸性粒细胞增多患者的血样，并通过酶联免疫吸附测定（ELISA）排泄分泌性犬弓首蛔虫抗原检测进行检测。我们在22%的病例中获得了阳性结果，在7%的病例中获得了强阳性结果。ELISA数据似乎与年龄有关，年龄较大的患者阳性结果更多（P < 0.0001）。实验室间阳性检测结果的分布在统计学上有显著差异（P < 0.0001），表明存在地区性来源。弓首蛔虫病的主要临床症状为：乏力、胃痛和肺部疾病。需要对这种人畜共患病进行个体和群体调查。
