Kolek V
Department of Pulmonary Medicine, University Hospital, Olomouc, Czech Republic.
Sarcoidosis. 1994 Sep;11(2):110-2.
Standard epidemiological and clinical features of sarcoidosis were evaluated in 24 regional centres from Moravia and Silesia (4 million inhabitants). During 1981-1990 the incidence ranged from 3.3 to 4.4/100,000 with slight decrease after 1985, when unselected chest X-ray screening was restricted. The prevalence (however disputable in sarcoidosis) increased from 41.3 to 63.1/100,000. Sex ratio male/female was 1: 2.35; only 39% of patients were younger than 40 years. Biopsy supported the diagnosis in 60% of cases. Tuberculin negativity was found in 64%. X-ray types were presented as follows: 0-2%, I-71%, II-22%, III-5%. Regional incidences varied from 0.9 to 11.7/100,000. Lower values were found in mining areas and high pneumoconiosis incidence. The course of the disease was benign with only sporadic extrapulmonary complications or pulmonary fibrosis. The results indicate that improved knowledge of sarcoidosis has brought epidemiological equilibrium to the evaluated area.
来自摩拉维亚和西里西亚（400万居民）的24个地区中心对结节病的标准流行病学和临床特征进行了评估。在1981年至1990年期间，发病率在3.3至4.4/10万之间，1985年未进行筛选的胸部X线检查受限后略有下降。患病率（然而在结节病中存在争议）从41.3/10万上升至63.1/10万。男女比例为1:2.35；只有39%的患者年龄小于40岁。活检在60%的病例中支持诊断。64%的患者结核菌素试验呈阴性。X线类型分布如下：0型-2%，I型-71%，II型-22%，III型-5%。各地区发病率在0.9至11.7/10万之间。在矿区和尘肺病高发地区发现较低的发病率。疾病进程呈良性，仅有散发性肺外并发症或肺纤维化。结果表明，对结节病认识的提高为评估地区带来了流行病学平衡。
