Pietinalho A, Hiraga Y, Hosoda Y, Löfroos A B, Yamaguchi M, Selroos O
Mjölbolsta Hospital, Finland.
Sarcoidosis. 1995 Mar;12(1):61-7.
Finland and Hokkaido resemble each other; the four season climate with cold winters and cool summers is the same as is the frequency of tuberculosis. The size of the population is almost the same. From the 1984 Japanese nationwide sarcoidosis survey we got the data from Hokkaido (288 patients) in order to compare the information with similarly collected data in Finland from 1984 (1,378 patients). The crude prevalence of sarcoidosis was 28.2 per 100,000 in Finland and 3.7 per 100,000 in Hokkaido. The annual incidence was 11.4 per 100,000 in Finland and 1.0 per 100,000 in Hokkaido. The sex distribution was similar; 63% vs 67% women in Finland and Hokkaido, respectively. At diagnosis the Hokkaidoan patients were significantly younger. In Hokkaido more cases were detected via mass X-ray survey (43% vs 34%). Among symptomatic patients eye symptoms were more frequent in Hokkaido, whereas respiratory and joint symptoms and erythema nodosum were more frequent in Finland. Bilateral hilar lymphadenopathy (BHL) was equally distributed (82% vs 84% whereas parenchymal lesions were seen more often in Finland (49% vs 25%) as well as peripheral lymphadenopathy (16% vs 8%).
芬兰和北海道有相似之处；四季分明，冬季寒冷、夏季凉爽，结核病发病率也相同。两地人口规模几乎相同。从1984年日本全国性结节病调查中，我们获取了北海道地区（288例患者）的数据，以便与1984年芬兰类似收集的数据（1378例患者）进行信息比较。芬兰结节病的粗患病率为每10万人28.2例，北海道为每10万人3.7例。芬兰的年发病率为每10万人11.4例，北海道为每10万人1.0例。性别分布相似，芬兰和北海道女性患者分别占63%和67%。在确诊时，北海道患者明显更年轻。在北海道，更多病例是通过大规模X线检查发现的（43%对34%）。有症状的患者中，北海道眼部症状更常见，而芬兰呼吸道和关节症状以及结节性红斑更常见。双侧肺门淋巴结肿大（BHL）分布相当（82%对84%），而实质性病变在芬兰更常见（49%对25%），外周淋巴结病变也是如此（16%对8%）。
