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关于目前结节病的流行病学知识水平。

Apropos of the present level of epidemiologic knowledge on sarcoidosis.

作者信息

Scharkoff T

机构信息

Department of Lung Diseases, BKH Cottbus, Kolkwitz/Cottbus, GDR.

出版信息

Sarcoidosis. 1987 Sep;4(2):152-4.

PMID:3659619
Abstract

Some particularities of the public health service in the GDR especially: 1) systematic unselected chest X-ray screening of the total population since 1954, 2) compulsory registration of sarcoidosis since 1961, 3) uniform, easily accessible and well developed medical care for all citizens represent the unique prerequisites for providing unbiased epidemiologic data in sarcoidosis. The author made use of the totally ascertained sarcoidosis population derived from the mass experiment as mentioned above and carried out an analytic study (cohort analysis of incident cases (n = 1575) adjusted for several variables. The incidence is the only parameter which is suitable for valuating the epidemiologic situation. The incidence/year ranged from 8.1 to 10.2/100,000 for a long period. Excessive ascertainment of the asymptomatic and transient forms does not contribute to the improvement of the medical care of the diseased persons. There is no reason to suppose an increase of the disease in the last 25 years. Recently the incidence curve is parallelly decreasing to the advanced restriction of the X-ray screening. Further relevant results are reviewed and some conclusions were drawn.

摘要

民主德国公共卫生服务的一些特点尤其包括

1)自1954年起对全体人口进行系统性的非选择性胸部X光筛查;2)自1961年起对结节病进行强制登记;3)为所有公民提供统一、便捷且完善的医疗服务,这些都是提供关于结节病无偏差流行病学数据的独特前提条件。作者利用了上述大规模实验中完全确定的结节病患者群体,并进行了一项分析研究(对1575例新发病例进行队列分析,并针对多个变量进行了调整)。发病率是评估流行病学状况的唯一合适参数。长期以来,年发病率在8.1至10.2/10万之间。过度确定无症状和短暂形式的病例无助于改善患病者的医疗护理。没有理由认为在过去25年中该病有所增加。最近,发病率曲线与X光筛查的进一步限制呈平行下降趋势。对其他相关结果进行了综述并得出了一些结论。

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