Senda M, Kanno I, Yonekura Y, Fujita H, Ishii K, Lyshkow H, Miura S, Oda K, Sadato N, Toyama H
Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Japan.
Ann Nucl Med. 1994 Aug;8(3):201-7. doi: 10.1007/BF03164998.
Identical sets of H2(15)O-PET brain activation data regarding vibrotactile stimulation and voluntary motion of the fingers in seven young normal subjects, together with the MRI, were analyzed in three PET centers by means of each center's own method of anatomical standardization to Talairach's frame. Every center used a linear or segmentally linear transformation with various number of scaling factors. A variation of 6-8 mm in each axis was observed in the foci localization due to the difference in the transformation principle and the measured brain size. Between-subject variation was similar in all the centers. Since different standardization methods define different coordinate systems, a cautious attitude should be taken to comparing results analyzed at different centers.
七个年轻正常受试者关于振动触觉刺激和手指自主运动的相同的H2(15)O-PET脑激活数据组，连同MRI，在三个PET中心通过各中心自身的Talairach框架解剖标准化方法进行了分析。每个中心都使用了具有不同数量缩放因子的线性或分段线性变换。由于变换原理和测量的脑尺寸的差异，在焦点定位中观察到每个轴上有6-8毫米的变化。各中心之间的受试者间差异相似。由于不同的标准化方法定义了不同的坐标系，因此在比较不同中心分析的结果时应持谨慎态度。
