Olivari A, Pradier R, Feierstein J, Guardo A, Glait H, Rojas A
J Surg Oncol. 1976;8(4):287-94. doi: 10.1002/jso.2930080405.
The immune reactivity of 100 head and neck cancer patients was studied by means of DNCB, candidine, blastic transformation with PHA, and lymphocyte counts. DNCB reactivity was strong in only 21% of the population and was found impaired in patients with advanced primitive tumors, with more than one primitive tumor, and in patients after radiation. Candidine reactivity was impaired in bigger primitive tumors, positive nodes, and advanced stages, as well as in postradiation patients. Blastic transformation was significantly worse in patients over 70 years and tended to be lower in patients with more than one primitive tumor. Good blastic transformation was also lowered in postradiation patients.
通过二硝基氯苯（DNCB）、白假丝酵母菌、PHA诱导的淋巴细胞转化及淋巴细胞计数等方法，对100例头颈癌患者的免疫反应性进行了研究。仅21%的患者DNCB反应性较强，且在晚期原发性肿瘤患者、有多个原发性肿瘤的患者以及放疗后的患者中发现其反应性受损。在较大的原发性肿瘤、阳性淋巴结、晚期患者以及放疗后的患者中，白假丝酵母菌反应性受损。70岁以上患者的淋巴细胞转化明显较差，且有多个原发性肿瘤的患者其淋巴细胞转化往往较低。放疗后患者的良好淋巴细胞转化也降低。
