加拿大魁北克省肺炎球菌对抗菌药物的耐药性
Pneumococcal resistance to antimicrobial agents in the province of Québec, Canada.
作者信息
Jetté L P, Ringuette L, Dascal A, Lapointe J R, Turgeon P
机构信息
Laboratoire de santé publique du Québec, Sainte-Anne-de-Bellevue, Canada.
出版信息
J Clin Microbiol. 1994 Oct;32(10):2572-5. doi: 10.1128/jcm.32.10.2572-2575.1994.
Abstract
The serogroup/serotypes (SGTs) and antimicrobial susceptibilities to 10 antimicrobial agents of 110 clinical strains of Streptococcus pneumoniae were determined. Strains intermediately resistant or highly resistant to penicillin G (80 of 110) belonged predominantly to SGTs 23 (45.0%), 19 (13.7%), 6 (10.0%), 9 (6.2%), and 14 (3.7%). The MICs of all cephalosporins, tetracycline, trimethoprim-sulfamethoxazole, and chloramphenicol increased along with the MICs of penicillin G. However, erythromycin resistance and clindamycin resistance were observed more frequently among the intermediately penicillin-resistant strains. Multiple resistance was observed for 32 strains, of which 25 were highly resistant to penicillin G and belong to SGT 23F. All strains were susceptible to vancomycin.
摘要
测定了110株肺炎链球菌临床分离株的血清群/血清型（SGTs）以及对10种抗菌药物的药敏情况。对青霉素G呈中度耐药或高度耐药的菌株（110株中的80株）主要属于血清群/血清型23（45.0%）、19（13.7%）、6（10.0%）、9（6.2%）和14（3.7%）。所有头孢菌素、四环素、甲氧苄啶-磺胺甲恶唑和氯霉素的最低抑菌浓度（MIC）均随青霉素G的MIC升高而升高。然而，在中度青霉素耐药菌株中，红霉素耐药和克林霉素耐药更为常见。观察到32株多重耐药菌株，其中25株对青霉素G高度耐药且属于血清型23F。所有菌株对万古霉素均敏感。
相似文献
1
Pneumococcal resistance to antimicrobial agents in the province of Québec, Canada.加拿大魁北克省肺炎球菌对抗菌药物的耐药性
J Clin Microbiol. 1994 Oct;32(10):2572-5. doi: 10.1128/jcm.32.10.2572-2575.1994.
2
Distribution of serotypes and antimicrobial resistance of Streptococcus pneumoniae strains isolated in Brazil from 1988 to 1992.1988年至1992年在巴西分离出的肺炎链球菌菌株的血清型分布及抗菌耐药性
J Clin Microbiol. 1994 Apr;32(4):906-11. doi: 10.1128/jcm.32.4.906-911.1994.
3
Serotype distribution of penicillin-resistant pneumococci and their susceptibilities to seven antimicrobial agents.耐青霉素肺炎球菌的血清型分布及其对七种抗菌药物的敏感性。
Antimicrob Agents Chemother. 1983 Mar;23(3):397-401. doi: 10.1128/AAC.23.3.397.
4
In vitro antibacterial activity of beta-lactams and non-beta-lactams against Streptococcus pneumoniae isolates from Sydney, Australia.β-内酰胺类和非β-内酰胺类药物对来自澳大利亚悉尼的肺炎链球菌分离株的体外抗菌活性。
Pathology. 2006 Aug;38(4):343-8. doi: 10.1080/00313020600820732.
5
Antimicrobial susceptibilities and serotypes of invasive Streptococcus pneumoniae strains in Switzerland.瑞士侵袭性肺炎链球菌菌株的抗菌药敏性及血清型
J Clin Microbiol. 1995 Dec;33(12):3159-63. doi: 10.1128/jcm.33.12.3159-3163.1995.
6
Antimicrobial resistance of invasive Streptococcus pneumoniae in Slovenia, 1993-1995. The Slovenian Meningitis Study Group.1993 - 1995年斯洛文尼亚侵袭性肺炎链球菌的耐药性。斯洛文尼亚脑膜炎研究小组。
Scand J Infect Dis. 1997;29(3):251-4. doi: 10.3109/00365549709019037.
7
Resistance patterns of streptococcus pneumoniae from carriers attending day-care centers in southwestern Greece.希腊西南部日托中心携带者肺炎链球菌的耐药模式。
Clin Infect Dis. 1997 Aug;25(2):188-94. doi: 10.1086/514526.
8
Susceptibilities of penicillin- and erythromycin-susceptible and -resistant pneumococci to HMR 3647 (RU 66647), a new ketolide, compared with susceptibilities to 17 other agents.将青霉素敏感及耐药、红霉素敏感及耐药的肺炎球菌对新型酮内酯类药物HMR 3647（RU 66647）的敏感性与对其他17种药物的敏感性进行比较。
Antimicrob Agents Chemother. 1998 Mar;42(3):624-30. doi: 10.1128/AAC.42.3.624.
9
Carriage of antibiotic-resistant Streptococcus pneumoniae in Greek infants and toddlers.希腊婴幼儿中耐抗生素肺炎链球菌的携带情况。
Eur J Clin Microbiol Infect Dis. 2000 Apr;19(4):288-93. doi: 10.1007/s100960050477.
引用本文的文献
1
Meningitis in a Canadian adult due to high level penicillin-resistant, cefotaxime-intermediate Streptococcus pneumoniae.一名加拿大成年人因对青霉素高度耐药、对头孢噻肟中度敏感的肺炎链球菌而患脑膜炎。
Can J Infect Dis. 1996 May;7(3):205-7. doi: 10.1155/1996/232985.
2
Reporting Emerging Resistance of Streptococcus pneumoniae from India.印度肺炎链球菌新出现的耐药性报告。
J Glob Infect Dis. 2010 Jan;2(1):10-4. doi: 10.4103/0974-777X.59245.
3
Surveillance of invasive Streptococcus pneumoniae infection in the province of Quebec, Canada, from 1996 to 1998: serotype distribution, Antimicrobial susceptibility, and clinical characteristics.1996年至1998年加拿大魁北克省侵袭性肺炎链球菌感染的监测：血清型分布、抗菌药物敏感性及临床特征
J Clin Microbiol. 2001 Feb;39(2):733-7. doi: 10.1128/JCM.39.2.733-737.2001.
4
Preventing pneumococcal disease.预防肺炎球菌疾病。
Can Fam Physician. 1998 Oct;44:2180-1, 2184-5.
5
Extremely high prevalence of nasopharyngeal carriage of penicillin-resistant Streptococcus pneumoniae among children in Kaohsiung, Taiwan.台湾高雄儿童中耐青霉素肺炎链球菌鼻咽部携带率极高。
J Clin Microbiol. 1998 Jul;36(7):1933-7. doi: 10.1128/JCM.36.7.1933-1937.1998.
6
7
Cefotaxime. A reappraisal of its antibacterial activity and pharmacokinetic properties, and a review of its therapeutic efficacy when administered twice daily for the treatment of mild to moderate infections.头孢噻肟。对其抗菌活性和药代动力学特性的重新评估，以及对其每日两次给药治疗轻至中度感染时的治疗效果的综述。
Drugs. 1997 Mar;53(3):483-510. doi: 10.2165/00003495-199753030-00009.
8
Distribution of capsular types and antibiotic susceptibility of invasive Streptococcus pneumoniae isolated from aborigines in central Australia.从澳大利亚中部原住民中分离出的侵袭性肺炎链球菌的荚膜类型分布及抗生素敏感性
J Clin Microbiol. 1996 Feb;34(2):338-41. doi: 10.1128/jcm.34.2.338-341.1996.
9
Evaluation of commercial methods for determining antimicrobial susceptibility of Streptococcus pneumoniae.用于确定肺炎链球菌抗菌药物敏感性的商业方法评估
J Clin Microbiol. 1996 Jan;34(1):10-4. doi: 10.1128/jcm.34.1.10-14.1996.
本文引用的文献
1
Infections due to penicillin-resistant pneumococci. Clinical, epidemiologic, and microbiologic features.耐青霉素肺炎球菌感染。临床、流行病学及微生物学特征。
Arch Intern Med. 1993 Jun 14;153(11):1301-10.
2
Susceptibility of 170 penicillin-susceptible and penicillin-resistant pneumococci to six oral cephalosporins, four quinolones, desacetylcefotaxime, Ro 23-9424 and RP 67829.170株青霉素敏感和耐药肺炎球菌对六种口服头孢菌素、四种喹诺酮类药物、去乙酰头孢噻肟、Ro 23 - 9424和RP 67829的敏感性
J Antimicrob Chemother. 1993 Feb;31(2):273-80. doi: 10.1093/jac/31.2.273.
3
Penicillin-resistant Streptococcus pneumoniae strains recovered in Houston: identification and molecular characterization of multiple clones.在休斯顿分离出的耐青霉素肺炎链球菌菌株：多个克隆株的鉴定及分子特征分析
J Infect Dis. 1993 Apr;167(4):850-6. doi: 10.1093/infdis/167.4.850.
4
Emergence of drug-resistant pneumococcal infections in the United States.美国耐药肺炎球菌感染的出现。
JAMA. 1994 Jun 15;271(23):1831-5.
5
Meningitis in a Canadian infant due to pneumococcus resistant to penicillin and chloramphenicol.一名加拿大婴儿因对青霉素和氯霉素耐药的肺炎球菌而患脑膜炎。
J Pediatr. 1983 Oct;103(4):580-2. doi: 10.1016/s0022-3476(83)80590-3.
6
Drug resistance patterns and serogroups or serotypes of pneumococcal isolates from cerebrospinal fluid or blood, 1979-1986.1979 - 1986年从脑脊液或血液中分离出的肺炎球菌菌株的耐药模式及血清群或血清型
J Infect Dis. 1988 Nov;158(5):956-64. doi: 10.1093/infdis/158.5.956.
7
Pneumococcal resistance to antibiotics.肺炎球菌对抗生素的耐药性。
Clin Microbiol Rev. 1990 Apr;3(2):171-96. doi: 10.1128/CMR.3.2.171.
8
Antimicrobial resistance of Streptococcus pneumoniae in the United States, 1979-1987. The Pneumococcal Surveillance Working Group.1979 - 1987年美国肺炎链球菌的抗菌药物耐药性。肺炎球菌监测工作组。
J Infect Dis. 1991 Jun;163(6):1273-8. doi: 10.1093/infdis/163.6.1273.
9
Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae isolates causing systemic infections in Spain, 1979-1989.1979 - 1989年西班牙引起全身感染的肺炎链球菌分离株的血清型分布及耐药性
Rev Infect Dis. 1991 Jan-Feb;13(1):56-60. doi: 10.1093/clinids/13.1.56.
10
Intercontinental spread of a multiresistant clone of serotype 23F Streptococcus pneumoniae.23F血清型肺炎链球菌多重耐药克隆株的洲际传播。
J Infect Dis. 1991 Aug;164(2):302-6. doi: 10.1093/infdis/164.2.302.
Zotero 插件