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质粒pKM101所决定的DNA修复系统在大肠杆菌recA和lex菌株中的表达。

Expression of the plasmid pKM101--determined DNA repair system in recA- and lex- strains of Escherichia coli.

作者信息

Monti-Bragadin C, Babudri N, Samer L

出版信息

Mol Gen Genet. 1976 Jun 15;145(3):303-6. doi: 10.1007/BF00325827.

DOI:10.1007/BF00325827
PMID:781517
Abstract

pKM101, a plasmid R factor of the N compatibility group increases methylmethane sulfonate mutagenesis and diminishes UV-killing in recA+ LEX+ and recA+ lex- strains, , but not in recA-lex+ strains. The induction of a "reclex" dependent colicin is not present in lex- strains carrying the pKM101 factor. These facts indicate that pKM101 acts through an error-prone DNA repair system which is recA+ dependent, but not lex+ dependent.

摘要

pKM101是N相容群的一种质粒R因子，它能增强甲基磺酸甲酯诱变作用，并减少recA⁺ LEX⁺和recA⁺ lex⁻菌株中的紫外线杀伤作用，但在recA⁻lex⁺菌株中则不然。携带pKM101因子的lex⁻菌株中不存在“reclex”依赖性大肠杆菌素的诱导。这些事实表明，pKM101通过一种易出错的DNA修复系统起作用，该系统依赖于recA⁺，但不依赖于lex⁺。

相似文献

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Expression of the plasmid pKM101--determined DNA repair system in recA- and lex- strains of Escherichia coli.质粒pKM101所决定的DNA修复系统在大肠杆菌recA和lex菌株中的表达。
Mol Gen Genet. 1976 Jun 15;145(3):303-6. doi: 10.1007/BF00325827.
2
Plasmid (pKM101)-mediated enhancement of repair and mutagenesis: dependence on chromosomal genes in Escherichia coli K-12.质粒（pKM101）介导的修复增强和诱变作用：对大肠杆菌K-12中染色体基因的依赖性
Mol Gen Genet. 1977 Mar 28;152(1):93-103. doi: 10.1007/BF00264945.
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Temperature sensitive R plasmid originated from Salmonella typhimurium.温度敏感型R质粒起源于鼠伤寒沙门氏菌。
Biochem Biophys Res Commun. 1974 Jul 10;59(1):361-9. doi: 10.1016/s0006-291x(74)80215-9.
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Frameshift mutagenesis by nitracrine analogues in wild-type, uvrB, polA and recA strains of Salmonella typhimurium, with and without plasmid pKM101.在有和没有质粒pKM101的情况下，硝吖啶类似物对鼠伤寒沙门氏菌野生型、uvrB、polA和recA菌株的移码诱变。
Mutat Res. 1987 Jul;184(1):13-21. doi: 10.1016/0167-8817(87)90031-9.
5
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Mutat Res. 1987 Jan;183(1):39-44. doi: 10.1016/0167-8817(87)90043-5.
6
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Repair promoted by plasmid pKM101 is different from SOS repair.质粒pKM101促进的修复与SOS修复不同。
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Plasmid (pKM101)-mediated Weigle reactivation in Escherichia coli K12 and Salmonella typhimurium LT2: genetic dependence, kinetics of induction, and effect of chloramphenicol.质粒（pKM101）介导的大肠杆菌K12和鼠伤寒沙门氏菌LT2中的韦格勒再活化：遗传依赖性、诱导动力学及氯霉素的影响
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UV protection and mutagenesis in uvrD, uvrE and recL strains of Escherichia coli carrying the pKM101 plasmid.携带pKM101质粒的大肠杆菌uvrD、uvrE和recL菌株中的紫外线防护与诱变作用
Mutat Res. 1979 Oct;62(3):451-7. doi: 10.1016/0027-5107(79)90040-x.

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Repair and plasmid R46 mediated mutation requires inducible functions in Proteus mirabilis.奇异变形杆菌中的修复和质粒R46介导的突变需要可诱导功能。
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3
The influence of colicinogenic plasmids ColIb-P9, ColIa-CA53 and ColV-K30 on the repair, mutagenesis and induction of colicin E1 synthesis.产大肠杆菌素质粒ColIb - P9、ColIa - CA53和ColV - K30对大肠杆菌素E1合成的修复、诱变及诱导的影响。

本文引用的文献

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Mutants of Escherichia coli requiring methionine or vitamin B12.需要甲硫氨酸或维生素B12的大肠杆菌突变体。
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