Gabbiani G, Trenchev P, Holborow E J
Lancet. 1975 Oct 25;2(7939):796-7. doi: 10.1016/s0140-6736(75)80008-0.
Human cells from skin and mammary-gland carcinomas show strong immunofluorescent staining with specific antibodies against smooth-muscle actin, myosin heavy meromyosin and light meromyosin, and contain numerous microfilaments as seen by electron microscopy. This increase in the amount of contractile proteins distinguishes cancer cells from the cells of normal tissues.