Ryng S, Duś D
Department of Organic Chemistry, Medical Academy, Wrocław, Poland.
Pharmazie. 1994 Oct;49(10):727-9.
Some new substituted 5-amino-3-methyl-4-ureidoisoxazoles and the 4-ethyl urethane of the 5-amino-3-methyl-isoxazole have been synthesized from 5-amino-3-methyl-4-isoxazolecarboxylic acid azide. Some representative ureides with primary, secondary, and heterocyclic amines were tested for their antileucemic activity.
由5-氨基-3-甲基-4-异恶唑羧酸叠氮化物合成了一些新的取代5-氨基-3-甲基-4-脲基异恶唑以及5-氨基-3-甲基异恶唑的4-乙基氨基甲酸酯。测试了一些具有伯胺、仲胺和杂环胺的代表性脲化物的抗白血病活性。
