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大剂量环磷酰胺治疗系统性红斑狼疮

[Treatment of systemic lupus erythematosis with high doses of cyclophosphamide].

作者信息

Baranowska-Daca E

机构信息

Kliniki Nefrologii Ak. Med., Lublinie.

出版信息

Wiad Lek. 1993 Nov;46(21-22):868-71.

PMID:7817583
Abstract

A case is presented of a female patient with systemic lupus erythematosus in whom a dramatic development was observed of life-threatening symptoms and signs from the central nervous system, haemopoietic system, and the kidneys. After introduction of therapy with high doses of cyclophosphamide administered in intravenous in combination with steroids, beneficial therapeutic effects were achieved. That suggests the conclusion that in early active form of lupus the risk of intensive treatment is acceptable.

摘要

本文报告了一例系统性红斑狼疮女性患者,该患者出现了来自中枢神经系统、造血系统和肾脏的危及生命的症状和体征的显著进展。在采用大剂量环磷酰胺静脉注射联合类固醇进行治疗后,取得了有益的治疗效果。这表明在狼疮的早期活动期,强化治疗的风险是可以接受的这一结论。

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