Oku H, Ishikawa S
Department of Ophthalmology, Osaka Medical College, Japan.
Br J Ophthalmol. 1994 Dec;78(12):912-6. doi: 10.1136/bjo.78.12.912.
The eye movements of 15 patients with Vogt-Koyanagi-Harada (VKH) syndrome were analysed. Transient dizziness occurred in 60% of the patients. Eight patients (53%) exhibited horizontal jerk nystagmus that was completely inhibited by visual fixation. Eight cases (53%) exhibited the elevation of vestibulo-ocular reflex (VOR) gain in darkness. Six of the patients with nystagmus had defective smooth pursuit movements with reduced gain on the side ipsilateral to the nystagmus. Saccadic and optokinetic eye movements were intact, and visual vestibular interaction was also normal. Impaired eye movements in VKH syndrome may be caused by asymmetry of the vestibular function secondary to the labyrinthine inflammation.
对15例Vogt-小柳-原田（VKH）综合征患者的眼球运动进行了分析。60%的患者出现短暂性头晕。8例患者（53%）表现出水平性急跳性眼球震颤，视觉注视可完全抑制该震颤。8例患者（53%）在黑暗中表现出前庭眼反射（VOR）增益升高。6例眼球震颤患者的平滑追踪运动存在缺陷，眼球震颤同侧的增益降低。扫视运动和视动性眼球运动正常，视觉前庭相互作用也正常。VKH综合征中眼球运动受损可能是由于迷路炎症继发的前庭功能不对称所致。
