John J, Björklund L J, Svenningsen N W, Jonson B
Department of Clinical Physiology, University Hospital, Lund, Sweden.
Acta Paediatr. 1994 Sep;83(9):903-9. doi: 10.1111/j.1651-2227.1994.tb13168.x.
Failure of neonatal patient triggered ventilation may reflect a delay in delivery of flow relative to the inspiratory effort of the infant. Transmission of diaphragmatic contraction to the sensor site (patient delay) and further transmission to and within the sensing device (device delay) both contribute to the delay in triggering. Patient and device delays were studied for different sensing systems in 36 infants, 24 of whom were intubated. Device delay was long (> 40 ms) with a conventional apnoea monitor compared with sensors placed at the airway opening (2 ms), the inspiratory (12 ms) and expiratory (3 ms) pressure transducers of the ventilator, the Graseby capsule (8 ms), strain gauges (3 ms) and oesophageal pressure (6 ms). In near normal infants, the sum of patient and device delays for the latter sensors was less than 20 ms and a minor component of the total delay. However, in severe lung disease the total delay may be more than 100 ms even for airway sensors.
新生儿患者触发通气失败可能反映出相对于婴儿吸气努力而言气流输送延迟。膈肌收缩传递至传感器部位（患者延迟），并进一步传递至传感装置及其内部（装置延迟），这两者都导致了触发延迟。对36例婴儿的不同传感系统进行了患者和装置延迟研究，其中24例婴儿进行了气管插管。与放置在气道开口处的传感器（2毫秒）、呼吸机吸气（12毫秒）和呼气（3毫秒）压力传感器、格拉塞比胶囊（8毫秒）、应变片（3毫秒）和食管压力（6毫秒）相比，传统呼吸暂停监测仪的装置延迟较长（>40毫秒）。在接近正常的婴儿中，后几种传感器的患者和装置延迟总和小于20毫秒，是总延迟的一小部分。然而，在严重肺部疾病中，即使对于气道传感器，总延迟也可能超过100毫秒。
