Hersh P S, Burnstein Y, Carr J, Etwaru G, Mayers M
Department of Ophthalmology, UMDNJ-New Jersey Medical School, Newark 07103, USA.
Ophthalmology. 1996 Aug;103(8):1210-22. doi: 10.1016/s0161-6420(96)30520-4.
To assess the different strategies and analyze clinical outcomes of excimer laser phototherapeutic keratectomy (PTK) for a variety of superficial corneal disorders.
Twenty-eight eyes of 26 patients with one of five general categories of corneal disorders were treated with a variety of PTK techniques. Patients were assessed for preoperative and postoperative corneal thickness, uncorrected and best spectacle-corrected visual acuity, refractive changes, corneal topography and astigmatism, and results of a subjective patient questionnaire. Follow-up ranged from 6 to 30 months.
The average number of laser pulses was 418, with a mean decrease in corneal thickness of 31 microns. Uncorrected visual acuity improved in 20 eyes and decreased in 5. Best spectacle-corrected visual acuity improved in 20 eyes and decreased in 5; two patients had two Snellen lines of best-corrected vision loss. Nineteen patients (21 eyes) noted symptomatic improvement. Corneal topography improved in 17 eyes and worsened in 1. The average refractive shift was +1.4 diopters; patients undergoing general PTK, PTK combined with mechanical superficial keratectomy, and superficial scar removal had greater degrees of hyperopic shift. Complications were rare. Two patients who did not appreciate adequate improvement in vision after PTK underwent subsequent penetrating keratoplasty.
A number of PTK techniques are available to treat particular corneal disorders. Planning of surgical strategy is guided by careful patient selection which will minimize optical side effects and optimize visual outcome and subjective symptomatology after the PTK procedure.
评估准分子激光光治疗性角膜切削术(PTK)治疗各种浅层角膜疾病的不同策略并分析临床结果。
26例患者的28只眼患有五种常见角膜疾病中的一种,接受了多种PTK技术治疗。对患者术前和术后的角膜厚度、未矫正和最佳矫正视力、屈光变化、角膜地形图和散光情况以及患者主观问卷结果进行评估。随访时间为6至30个月。
平均激光脉冲数为418次,角膜厚度平均减少31微米。20只眼的未矫正视力提高,5只眼下降。20只眼的最佳矫正视力提高,5只眼下降;2例患者最佳矫正视力下降两行。19例患者(21只眼)症状改善。17只眼角膜地形图改善,1只眼恶化。平均屈光变化为+1.4屈光度;接受常规PTK、PTK联合机械性浅层角膜切除术和浅层瘢痕切除术的患者远视性移位程度更大。并发症罕见。2例PTK术后视力改善不明显的患者随后接受了穿透性角膜移植术。
有多种PTK技术可用于治疗特定的角膜疾病。手术策略的规划以仔细的患者选择为指导,这将使光学副作用最小化,并优化PTK术后的视觉效果和主观症状。