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儿童良性慢性大疱性皮肤病。基底膜上线性IgA和C3沉积。

Benign chronic bullous dermatosis of childhood. Linear IgA and C3 deposition on the basement membrane.

作者信息

Prystowsky S, Gilliam J N

出版信息

Arch Dermatol. 1976 Jun;112(6):837-8.

PMID:782363
Abstract

Benign chronic bullous dermatosis of childhood (BCBDC) is characterized by predominantly monomorphous, large, tense bullae with a predilection for the lower part of the trunk, the pelvic region, and the lower extremities. Most patients have blisters for two to three years and experience spontaneous exacerbations and remissions. We report the first case known to us in which a linear bank of IgA (but no lgG or lgM) and complement was found at the epidermal basal lamina as demonstrated by immunofluorescence studies.

摘要

儿童良性慢性大疱性皮肤病(BCBDC)的特征主要为单形性、大的、紧张性水疱,好发于躯干下部、盆腔区域及下肢。大多数患者水疱持续两到三年,且病情有自发的加重和缓解。我们报告了我们所知的首例病例,免疫荧光研究显示在表皮基底层发现了一条IgA(但无IgG或IgM)和补体的线性带。

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