编码褐家鼠主要穹窿蛋白的cDNA序列。
The sequence of a cDNA encoding the major vault protein from Rattus norvegicus.
作者信息
Kickhoefer V A, Rome L H
机构信息
Department of Biological Chemistry, University of California School of Medicine, Los Angeles 90024-1737.
出版信息
Gene. 1994 Dec 30;151(1-2):257-60. doi: 10.1016/0378-1119(94)90667-x.
PMID:7828886
Abstract
We have isolated a cDNA clone encoding the 104-kDa major vault protein (MVP) from Rattus norvegicus. The complete nucleotide sequence was determined. Comparison of the deduced amino acid (aa) sequence to that of MvpA from Dictyostelium discoideum revealed that the proteins share about 57% aa identity. Southern blot analysis indicates that the rat MVP is a single-copy gene.
摘要
我们从褐家鼠中分离出了一个编码104 kDa主要穹窿蛋白（MVP）的cDNA克隆。测定了其完整的核苷酸序列。将推导的氨基酸（aa）序列与盘基网柄菌的MvpA序列进行比较，发现这两种蛋白质的氨基酸同一性约为57%。Southern印迹分析表明，大鼠MVP是一个单拷贝基因。
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