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1
Viscosimetric effect of fibrinogen.纤维蛋白原的粘度测定效应
J Clin Pathol. 1994 Nov;47(11):1004-5. doi: 10.1136/jcp.47.11.1004.
2
A viscometric method of measuring plasma fibrinogen concentration.一种测量血浆纤维蛋白原浓度的粘度测定法。
J Clin Pathol. 1993 Apr;46(4):380. doi: 10.1136/jcp.46.4.380-b.
3
On the aggregation of red cells in Waldenström's macroglobulinaemia and multiple myeloma.关于瓦尔登斯特伦巨球蛋白血症和多发性骨髓瘤中红细胞的聚集
Microvasc Res. 1975 May;9(3):279-86. doi: 10.1016/0026-2862(75)90064-3.
4
Plasma volume expansion and increased serum viscosity in myeloma and macroglobulinaemia.骨髓瘤和巨球蛋白血症中的血浆容量扩张及血清粘度增加。
Clin Exp Immunol. 1974 Feb;16(2):169-76.
5
[Blood hyperviscosity syndromes].
Ric Clin Lab. 1983;13 Suppl 3:89-104.
6
Plasmapheresis for hyperviscosity syndrome in macroglobulinemia Waldenström and multiple myeloma: influence on blood rheology and the microcirculation.用于华氏巨球蛋白血症和多发性骨髓瘤高黏滞综合征的血浆置换：对血液流变学和微循环的影响
J Lab Clin Med. 1992 Jan;119(1):69-76.
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The viscosity of blood, plasma and serum in dys- and paraproteinemias.异常蛋白血症和副蛋白血症中血液、血浆及血清的黏度
Acta Med Scand Suppl. 1966;456:1-97.
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[Serum or plasma viscosimetry in normal subjects, cord blood and patients with paraproteinemias].
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A hypothesis of plasma "atomosphere" around the red cells in patients with Waldenström's macroglobulinemia and multiple myeloma: A deduction from viscosity study.关于华氏巨球蛋白血症和多发性骨髓瘤患者红细胞周围血浆“大气层”的假说：基于黏度研究的推断
Microvasc Res. 1976 May;11(3):325-34. doi: 10.1016/0026-2862(76)90062-5.
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Hyperviscosity syndrome in paraproteinemia. Managed by plasma exchange; monitored by serum tests.副蛋白血症中的高黏滞综合征。通过血浆置换进行治疗；通过血清检测进行监测。
Transfusion. 1982 Jan-Feb;22(1):51-3. doi: 10.1046/j.1537-2995.1982.22182154217.x.

引用本文的文献

1
Fibrinogen is not a prognostic factor for response to HELP-apheresis in sudden sensorineural hearing loss (SSHL).纤维蛋白原不是突发性感音神经性听力损失（SSHL）患者对血液成分单采治疗（HELP-apheresis）反应的预后因素。
Eur Arch Otorhinolaryngol. 2015 Dec;272(12):3693-703. doi: 10.1007/s00405-014-3449-9. Epub 2014 Dec 20.
2
Recurring extracorporeal circuit clotting during continuous renal replacement therapy resolved after single-session therapeutic plasma exchange.在持续肾脏替代治疗期间反复出现的体外循环凝血在单次治疗性血浆置换后得到解决。
J Clin Apher. 2011;26(4):214-5. doi: 10.1002/jca.20291. Epub 2011 May 26.

本文引用的文献

1
PLASMA VISCOSITY IN CLINICAL LABORATORY PRACTICE.临床实验室实践中的血浆粘度
J Med Lab Technol. 1965 Apr;22:70-3.
2
A quick and accurate method for the determination of fibronogen in plasma.一种快速准确测定血浆中纤维蛋白原的方法。
J Lab Clin Med. 1961 Sep;58:477-88.
3
The viscosimetric determination of blood fibrinogen.血液纤维蛋白原的粘度测定法
J Lab Clin Med. 1953 Oct;42(4):641-5.
4
A viscometric method of measuring plasma fibrinogen concentration.一种测量血浆纤维蛋白原浓度的粘度测定法。
J Clin Pathol. 1993 Apr;46(4):380. doi: 10.1136/jcp.46.4.380-b.
5
Predictive value of paired plasma and serum viscosity in early rheumatic conditions.配对血浆和血清粘度在早期风湿性疾病中的预测价值。
Br Med J (Clin Res Ed). 1981 Apr 11;282(6271):1198. doi: 10.1136/bmj.282.6271.1198.
6
Relationship between paired plasma and serum viscosity and plasma proteins in the horse.马的配对血浆与血清粘度和血浆蛋白之间的关系。
Res Vet Sci. 1984 May;36(3):360-3.
7
Blood-plasma viscosity: an approximate temperature-invariant arising from generalised concepts.血浆黏度：源于广义概念的近似温度不变量。
Biorheology. 1970 Jan;6(3):169-87. doi: 10.3233/bir-1970-6304.
8
The viscosity of blood, plasma and serum in dys- and paraproteinemias.异常蛋白血症和副蛋白血症中血液、血浆及血清的黏度
Acta Med Scand Suppl. 1966;456:1-97.
9
Prognostic significance of rheological and biochemical findings in patients with intermittent claudication.间歇性跛行患者血流变学和生化检查结果的预后意义
Br Med J. 1973 Dec 8;4(5892):581-3. doi: 10.1136/bmj.4.5892.581.
10
Clinical, haemodynamic, rheological, and biochemical findings in 126 patients with intermittent claudication.126例间歇性跛行患者的临床、血流动力学、流变学及生化检查结果
Br Med J. 1973 Dec 8;4(5892):576-81. doi: 10.1136/bmj.4.5892.576.

纤维蛋白原的粘度测定效应

Viscosimetric effect of fibrinogen.

作者信息

Lane D W, l'Anson S

机构信息

Department of Haematology, Scarborough Hospital, North Yorks.

出版信息

J Clin Pathol. 1994 Nov;47(11):1004-5. doi: 10.1136/jcp.47.11.1004.

DOI:10.1136/jcp.47.11.1004
PMID:7829672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC503061/
Abstract

AIMS

To investigate the correlation between fibrinogen concentration and plasma and serum viscosity.

METHODS

Measurements of paired plasma viscosity and serum viscosity were compared in 45 subjects with a considerable range of fibrinogen concentrations and serum viscosity.

RESULTS

Plasma and serum viscosity correlated well with plasma fibrinogen in cases of normal serum viscosity, but not in cases of myeloma or macroglobulinaemia. When an exponential correlation between plasma and serum viscosity was used, fibrinogen showed a good correlation in both normal and abnormal conditions.

CONCLUSIONS

There is an exponential correlation between plasma and serum viscosity which depends on the plasma fibrinogen concentration. This is in accordance with Arrhenius's formula for solutions of varying concentrations.

摘要

目的

研究纤维蛋白原浓度与血浆及血清黏度之间的相关性。

方法

对45名纤维蛋白原浓度和血清黏度范围差异较大的受试者进行配对血浆黏度和血清黏度测量，并进行比较。

结果

在血清黏度正常的情况下，血浆和血清黏度与血浆纤维蛋白原相关性良好，但在骨髓瘤或巨球蛋白血症患者中并非如此。当采用血浆与血清黏度之间的指数相关性时，纤维蛋白原在正常和异常情况下均显示出良好的相关性。

结论

血浆和血清黏度之间存在指数相关性，该相关性取决于血浆纤维蛋白原浓度。这与阿伦尼乌斯关于不同浓度溶液的公式相符。