纤维蛋白原的粘度测定效应
Viscosimetric effect of fibrinogen.
作者信息
Lane D W, l'Anson S
机构信息
Department of Haematology, Scarborough Hospital, North Yorks.
出版信息
J Clin Pathol. 1994 Nov;47(11):1004-5. doi: 10.1136/jcp.47.11.1004.
AIMS
To investigate the correlation between fibrinogen concentration and plasma and serum viscosity.
METHODS
Measurements of paired plasma viscosity and serum viscosity were compared in 45 subjects with a considerable range of fibrinogen concentrations and serum viscosity.
RESULTS
Plasma and serum viscosity correlated well with plasma fibrinogen in cases of normal serum viscosity, but not in cases of myeloma or macroglobulinaemia. When an exponential correlation between plasma and serum viscosity was used, fibrinogen showed a good correlation in both normal and abnormal conditions.
CONCLUSIONS
There is an exponential correlation between plasma and serum viscosity which depends on the plasma fibrinogen concentration. This is in accordance with Arrhenius's formula for solutions of varying concentrations.
目的
研究纤维蛋白原浓度与血浆及血清黏度之间的相关性。
方法
对45名纤维蛋白原浓度和血清黏度范围差异较大的受试者进行配对血浆黏度和血清黏度测量，并进行比较。
结果
在血清黏度正常的情况下，血浆和血清黏度与血浆纤维蛋白原相关性良好，但在骨髓瘤或巨球蛋白血症患者中并非如此。当采用血浆与血清黏度之间的指数相关性时，纤维蛋白原在正常和异常情况下均显示出良好的相关性。
结论
血浆和血清黏度之间存在指数相关性，该相关性取决于血浆纤维蛋白原浓度。这与阿伦尼乌斯关于不同浓度溶液的公式相符。
Zotero 插件