McCarthy W J, Caskey N H, Jarvik M E, Gross T M, Rosenblatt M R, Carpenter C
Department of Psychology, University of California, Los Angeles (UCLA) 90024-1563.
Am J Public Health. 1995 Jan;85(1):67-72. doi: 10.2105/ajph.85.1.67.
The purpose of this study was to examine intraindividual differences in smoking behavior between smoking regular and mentholated cigarettes.
Healthy male smokers (n = 29) smoked either a regular or a mentholated cigarette in two separate sessions 1 week apart. Commercial brands with comparable tar, nicotine, and CO content were used. Smoking behavior was constrained by fixed 15-second interpuff intervals, but puff volume and number of puffs were unconstrained.
When smoking the non-mentholated brand of cigarettes, participants smoked 22% more puffs and had 13% higher mean volumes per puff than they did when smoking the mentholated brand of cigarettes. The aggregate 39% excess exposure to cigarette smoke in the regular-cigarette condition was not accompanied by commensurate excesses in expired carbon monoxide or in physiological measures normally correlated with nicotine exposure.
These findings parallel differences in physiological correlates of exposure to nicotine found in cross-sectional comparisons of African-American and White smokers and are consistent with the results of emerging laboratory investigations.
本研究旨在探讨吸常规香烟和薄荷醇香烟的个体在吸烟行为上的个体内差异。
29名健康男性吸烟者在相隔1周的两个独立时段分别吸一支常规香烟或一支薄荷醇香烟。使用焦油、尼古丁和一氧化碳含量相当的商业品牌香烟。吸烟行为受固定的15秒吸 puff 间隔限制，但 puff 量和 puff 次数不受限制。
与吸薄荷醇香烟时相比，参与者吸非薄荷醇香烟品牌时，puff 次数多22%，每次 puff 的平均量高13%。在吸常规香烟的情况下，香烟烟雾总暴露量多出39%，但呼出一氧化碳或通常与尼古丁暴露相关的生理指标并未相应增加。
这些发现与非裔美国吸烟者和白人吸烟者横断面比较中发现的尼古丁暴露生理相关性差异相似，并且与新出现的实验室研究结果一致。
