LiVolsi V A
Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia 19104.
Thyroid. 1994 Fall;4(3):333-9. doi: 10.1089/thy.1994.4.333.
Lymphocytic infiltration of the thyroid gland is the pathologic hallmark of autoimmune thyroid disease. Lymphoid cells are seen in the stroma of glands affected by Graves' disease. However, large lymphoid infiltrates are characteristic of that spectrum of diseases conveniently termed chronic lymphocytic thyroiditis. In this review, the pathology of the various subtypes of chronic thyroiditis is enumerated, including recently defined lesions, i.e., painless thyroiditis, thyroiditis associated with interleukin chemotherapy, and peritumor thyroiditis are reviewed. The unifying morphologic characteristics seen in these conditions are discussed.
甲状腺的淋巴细胞浸润是自身免疫性甲状腺疾病的病理标志。在格雷夫斯病累及的腺体间质中可见淋巴细胞。然而，大量淋巴细胞浸润是一组方便称为慢性淋巴细胞性甲状腺炎的疾病谱的特征。在本综述中，列举了慢性甲状腺炎各亚型的病理学，包括最近定义的病变，即无痛性甲状腺炎、与白细胞介素化疗相关的甲状腺炎和肿瘤周围甲状腺炎。讨论了在这些情况下所见的统一形态学特征。
