Fang J
Nuclear medicine laboratory, Shanghai College of Traditional Chinese Medicine.
Zhen Ci Yan Jiu. 1994;19(1):42-5.
We observed cyclic nucleotide content of plasma, brain and Spleen tissues when analgesia was produced by acupuncture at the Zusanli. The restrained group without acupuncture was as blank control and acupuncture at Taichong as acupuncture control. We found that after acupuncture at Zusanli the concentration of cyclic nucleotide in plasma was increased significantly (P < 0.05) and the cAMP concentration of spleen had a tendency of enhancement, but the content of cAMP in the cortex had a tendency of decrease. The concentration of cAMP, cGMP and its ratio cAMP/cGMP was different in cortex and spinal cord between acupuncture at Zusanli and Taichong groups. These results showed that acupuncture at Zusanli and Taichong could induce different changes of concentration of cAMP and cGMP.
我们观察了针刺足三里产生镇痛作用时血浆、脑和脾脏组织中环核苷酸的含量。未针刺的束缚组作为空白对照，针刺太冲作为针刺对照。我们发现，针刺足三里后血浆中环核苷酸浓度显著升高（P < 0.05），脾脏中cAMP浓度有升高趋势，但皮层中cAMP含量有下降趋势。足三里组与太冲组在皮层和脊髓中cAMP、cGMP浓度及其比值cAMP/cGMP存在差异。这些结果表明，针刺足三里和太冲可引起cAMP和cGMP浓度的不同变化。
