Tishler M, Aharon A, Ehrenfeld M, Avni I, Bendet E, Bombardieri S, Yaron M, Shoenfeld Y
Department of Rheumatology, Elias Sourasky Medical Center, Ichilov Hospital, Tel Hashomer.
Clin Rheumatol. 1994 Sep;13(3):438-41. doi: 10.1007/BF02242939.
Sixty Israeli patients, 30 with primary Sjögren's syndrome (SS) and 30 with rheumatoid arthritis (RA) and secondary SS, were evaluated. The Schirmer-1 test and a positive labial salivary gland biopsy were found to be the most helpful tools in assessing the diagnosis of SS. Extraglandular features such as Raynaud's phenomenon, lymphadenopathy and CNS involvement as well as parotid gland enlargement (p < 0.05) were more common in primary SS. Antinuclear antibodies, especially anti-Ro (SSA) and anti-La (SSB) were also more common in primary SS (p < 0.05). Our results are in accord with those of many European centers, despite the different genetic background.
对60名以色列患者进行了评估，其中30名患有原发性干燥综合征（SS），30名患有类风湿性关节炎（RA）及继发性SS。发现施默尔-1试验和唇唾液腺活检阳性是评估SS诊断最有用的工具。原发性SS中，诸如雷诺现象、淋巴结病、中枢神经系统受累以及腮腺肿大等腺外特征更为常见（p<0.05）。抗核抗体，尤其是抗Ro（SSA）和抗La（SSB）在原发性SS中也更为常见（p<0.05）。尽管存在不同的遗传背景，但我们的结果与许多欧洲中心的结果一致。
