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患有和未患有HIV-1的肯尼亚肺结核患者的临床和免疫标志物

Clinical and immunological markers in Kenyan pulmonary tuberculosis patients with and without HIV-1.

作者信息

Kivihya-Ndugga L E, Ochola J J, Otieno G, Muthami L N, Gathua S

机构信息

Diseases Research Unit, Kenya Medical Research Institute, Nairobi.

出版信息

East Afr Med J. 1994 Jun;71(6):373-5.

PMID:7835258
Abstract

Amongst newly diagnosed pulmonary tuberculosis patients, 44% were co-infected with human immunodeficiency virus (HIV). Pulmonary tuberculosis patients with HIV-1 presented more frequently with lymphadenopathy and diarrhoea than those without HIV-1. Peripheral blood CD4+ counts were significantly lower in patients with pulmonary tuberculosis with HIV-1 than those with pulmonary tuberculosis alone, P = 0.0292. CD4+ lymphocyte counts, lymphadenopathy and BCG scar could serve as indicators of HIV-1 infection in pulmonary tuberculosis (PTB) patients.

摘要

在新诊断的肺结核患者中,44%合并感染了人类免疫缺陷病毒(HIV)。与未感染HIV-1的肺结核患者相比,感染HIV-1的肺结核患者更常出现淋巴结病和腹泻。HIV-1感染的肺结核患者外周血CD4+计数显著低于单纯肺结核患者,P = 0.0292。CD4+淋巴细胞计数、淋巴结病和卡介苗瘢痕可作为肺结核(PTB)患者HIV-1感染的指标。

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